Cochrane · systematic review · CD011695

Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and middle‐income countries (LMIC)

Goudet, SM, Bogin, BA, Madise, NJ, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Public HealthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
13
current version
GRADE rated
13
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 15.4%Low 8 · 61.5%Moderate 3 · 23.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Zinc supplementation in pregnant women versus supplementation without zinc or placebo to reduce stunting in children (low birth weight, length at birth and at 12 months)

Population: pregnant women
3 questions
OutcomeEffectEvidenceStatus / GRADE
Length (cm) at birth
Zinc supplementation in pregnant women vs supplementation without zinc or placebo to reduce stunting
no estimate extracted2 studies · 1337 participantsModerate
Downgraded: risk of bias, indirectness
Length (cm) at 12 months
Zinc supplementation in pregnant women vs supplementation without zinc or placebo to reduce stunting
no estimate extracted1 study · 237 participantsLow
Downgraded: risk of bias, indirectness
Low birth weight (g)
Zinc supplementation in pregnant women vs supplementation without zinc or placebo to reduce stunting
no estimate extracted2 studies · 1367 participantsModerate
Downgraded: risk of bias, indirectness

Micronutrient or macronutrient supplementation interventions in children versus no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Population: children under 5 years old
6 questions
OutcomeEffectEvidenceStatus / GRADE
Height‐for‐age (z‐score)
Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)
no estimate extracted3 studies · 2601 participantsLow
Downgraded: risk of bias, inconsistency
Height‐for‐age (z‐score) Length gain (6 months)
Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)
no estimate extracted1 study · 653 participantsLow
Downgraded: risk of bias, indirectness
Height‐for‐age (%) at 18 months, 21 months Length gain
Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)
no estimate extracted1 study · 324 participantsModerate
Downgraded: risk of bias, indirectness
Length velocity (change in cm since start of supplementation)
Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)
no estimate extracted1 study · 315 participantsLow
Downgraded: risk of bias, indirectness
Length velocity (cm/month)
Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)
MD 0.22 [0.02, 0.43]1 study · 75 participantsVery low
Downgraded: risk of bias, indirectness
Length (cm) at 12 months
Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)
MD 2.31 study · 100 participantsLow
Downgraded: risk of bias, indirectness

Nutrition education intervention for pregnant women versus standard care or no intervention, to reduce stunting in children (low birth weight)

Population: pregnant women
1 question
OutcomeEffectEvidenceStatus / GRADE
Low birth weight (g)
Nutrition education intervention for pregnant women vs standard care or no intervention, to reduce stunting
MD 478.44 [423.55, 533.32]2 studies · 415 participantsLow
Downgraded: risk of bias, indirectness

Nutrition systems strengthening interventions targeting children compared with no intervention or standard care to reduce stunting (height‐for‐age, length at 18 months)

Population: children under 5 years old
3 questions
OutcomeEffectEvidenceStatus / GRADE
Height‐for‐age (z‐score) at 18 months
Nutrition systems strengthening interventions targeting children vs no intervention or standard care to reduce stunting (height‐for‐age, length at 18 months)
MD 0.386 [0.209, 0.562]1 study · 377 participantsLow
Downgraded: risk of bias, indirectness
Height‐for‐age (z‐score)
Nutrition systems strengthening interventions targeting children vs no intervention or standard care to reduce stunting (height‐for‐age, length at 18 months)
no estimate extracted1 study · 999 participantsVery low
Downgraded: risk of bias, indirectness
Length (cm) at 18 months
Nutrition systems strengthening interventions targeting children vs no intervention or standard care to reduce stunting (height‐for‐age, length at 18 months)
MD 1.068 [0.488, 1.648]1 study · 377 participantsLow
Downgraded: risk of bias, indirectness