Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Lifestyle interventions vs control ‐ Maternal outcomes

Postnatal weight retention or return to pre‐pregnancy weight · women with gestational diabetes mellitus

Lifestyle interventions may leads to higher postnatal weight retention or return to pre‐pregnancy weight compared with control ‐ Maternal outcomes (low certainty).

1 finding from 1 review

Lifestyle vs control ‐ Neonatal and later outcomes

Perinatal (fetal and neonatal death) and later infant mortality · women with gestational diabetes mellitus

Lifestyle showed no clear difference in perinatal (fetal and neonatal death) and later infant mortality compared with control ‐ Neonatal and later outcomes (low certainty).

1 finding from 1 review

Remifentanil (PCA) vs another opioid (PCA)

Additional analgesia required (escape analgesia) · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in additional analgesia required (escape analgesia) compared with another opioid (PCA) (low certainty).

1 finding from 1 review

Remifentanil (PCA) vs epidural/CSE

Maternal respiratory depression (< 9, < 8 breaths/min) · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in maternal respiratory depression (< 9, < 8 breaths/min) compared with epidural/CSE (low certainty).

1 finding from 1 review