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Evidence found and GRADE certainty

2,745 questions · 4,389 findings · 203 reviews · Oral Health

No studies found 39 · 0.9%GRADE not reported 3,844 · 87.6%Very low 198 · 4.5%Low 137 · 3.1%Moderate 134 · 3.1%High 37 · 0.8%

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

About 56% of 5-6 year-old children in Latin America and the Caribbean had dental caries in primary teeth (95% CI 52-59%); certainty not graded.

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Mean number of decayed teeth (mean DT) · Older people (aged 60 years or older) with dementia

Decayed-teeth values varied across studies and were not meta-analyzed.

1 finding from 1 review

30% silver diamine fluoride vs Not specified

Arrest of dentine caries · Children with active dentine caries in primary teeth

One study reported 30% silver diamine fluoride effectively arrested dentine caries in primary teeth; ungraded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In Brazil, pooled permanent-teeth caries prevalence in 11-13 year-olds was 56% (95% CI 53-60%), with a significant declining trend over time; certainty not graded.

1 finding from 1 review

12% silver diamine fluoride (SDF), single (one-off) application vs Not specified

Arrest of dentine caries · Children with active dentine caries

One trial found a single application of 12% silver diamine fluoride did not arrest dentine caries; ungraded.

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Patient outcomes: mean number of filled teeth per 0- to 15-year-old · Older people (aged 60 years or older) with dementia

Filled-teeth values varied across studies and were not meta-analyzed.

1 finding from 1 review

High maternal allostatic load (chronic stress) and low socioeconomic status vs Lower maternal allostatic load

Dental caries in children · Mother-child pairs

In one cross-sectional study, higher maternal allostatic load was associated with child dental caries experience and with health-related maternal care-taking behaviours; not pooled (ungraded).

1 finding from 1 review

Selective or stepwise carious tissue removal vs Non-selective or complete carious tissue removal

Barriers and facilitators of SE/SW utilization · Dentists managing deep carious lesions in permanent vital teeth

Dentists' use of selective or stepwise removal was shaped by their age and understanding of caries, professional guidelines, peers and professional identity, financial and regulatory incentives, and beliefs about how treatments perform, identified by thematic analysis mapped to the TDF and Behavior Change Wheel (ungraded).

1 finding from 1 review

10% silver diamine fluoride (SDF) vs Glass ionomer restoration and tooth-brushing

Remineralisation of early enamel caries · Children with early enamel caries in erupting permanent first molars

One pilot study found 10% silver diamine fluoride worked about as well as glass ionomer restoration and tooth-brushing for remineralising early enamel caries; ungraded.

1 finding from 1 review

0.9% silicon tetrafluoride (SiF4) vs Not specified

Remineralisation of white spot lesions · Patients (mainly children) with white spot lesions (WSL)

One trial found professionally applied silicon tetrafluoride did not remineralise white spot lesions; ungraded.

1 finding from 1 review

6% sodium fluoride with 6% calcium fluoride varnish vs no treatment

Remineralisation of early enamel caries · Children with early enamel caries (permanent dentition)

One trial found 6% sodium fluoride plus 6% calcium fluoride varnish significantly reversed early enamel caries versus no treatment; ungraded and not meta-analysed.

1 finding from 1 review

Low socioeconomic status and family financial stress vs Higher socioeconomic status and lower stress

Salivary cortisol, cariogenic bacterial load and dental caries · Kindergarten-age children

In one cross-sectional study of children, low socioeconomic status, higher basal salivary cortisol and higher cariogenic bacterial counts were each independently associated with higher dental caries risk; not pooled (ungraded).

1 finding from 1 review

Selective or stepwise carious tissue removal vs Non-selective or complete carious tissue removal

Temporal change in the proportion of dentists utilizing SE/SW · Dentists managing deep carious lesions in permanent vital teeth

The proportion of dentists choosing selective or stepwise removal rose significantly over time, by about 1.6% per calendar year (meta-regression, p<0.05), a trend the authors described as borderline (ungraded).

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

About 58% of 11-13 year-old children in Latin America and the Caribbean had dental caries in permanent teeth (95% CI 54-61%); certainty not graded.

1 finding from 1 review

Low socioeconomic position and adverse behavioural factors vs Higher socioeconomic position and fewer adverse behaviours

Systemic inflammation (C-reactive protein) and periodontal disease progression · General-population adults (German cohort)

In one 5-year longitudinal study, accumulation of low socioeconomic and behavioural factors was associated with greater periodontal disease progression and higher C-reactive protein; not pooled (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Mean number of missing teeth in OC cases vs controls · Older people (aged 60 years or older) with dementia

Missing-teeth values varied across studies and were not meta-analyzed.

1 finding from 1 review