Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Oral anti‐diabetic pharmacological therapies vs placebo (outcomes

Perineal trauma · women diagnosed with gestational diabetes; 24‐30 weeks' gestation; singleton pregnancy.

It is very uncertain whether oral anti‐diabetic pharmacological therapies changes perineal trauma compared with placebo ‐ maternal outcomes (very low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies vs placebo (outcomes

Induction of labour · women diagnosed with gestational diabetes; 24‐30 weeks' gestation; singleton pregnancy.

It is very uncertain whether oral anti‐diabetic pharmacological therapies changes induction of labour compared with placebo ‐ maternal outcomes (very low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies vs placebo (outcomes

Large‐for‐gestational age · Infants of women diagnosed with gestational diabetes

It is very uncertain whether oral anti‐diabetic pharmacological therapies changes large‐for‐gestational age compared with placebo ‐ neonatal outcomes (very low certainty).

1 finding from 1 review

Lifestyle interventions vs control ‐ Maternal outcomes

Hypertensive disorders of pregnancy: pre‐eclampsia · women with gestational diabetes mellitus

Lifestyle interventions showed no clear difference in hypertensive disorders of pregnancy (pre‐eclampsia) compared with control ‐ Maternal outcomes (low certainty).

1 finding from 1 review

Lifestyle vs control ‐ Neonatal and later outcomes

Composite outcome in infant (death, shoulder dystocia, nerve palsy, bone fracture) · women with gestational diabetes mellitus

It is very uncertain whether lifestyle changes composite outcome in infant (death, shoulder dystocia, nerve palsy,… compared with control ‐ Neonatal and later outcomes (very low certainty).

1 finding from 1 review

Lifestyle vs control ‐ Neonatal and later outcomes

Adiposity (child) ‐ Childhood BMI > 85th percentile · women with gestational diabetes mellitus

Lifestyle showed no clear difference in adiposity (child) ‐ Childhood BMI > 85th percentile compared with control ‐ Neonatal and later outcomes (moderate certainty).

1 finding from 1 review