Prevalence of untreated decay (% DT > 0) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States
In United States, secondary versus university education differed by 10.4 percentage points in prevalence of untreated decay.
4 findings from 1 review
AD 10.4 [4.7, 16.2]
1 study · 4568 participants
GRADE not reported
AD 15.2 [8.8, 21.6]
1 study · 3278 participants
GRADE not reported
AD 14.1 [5.1, 23.1]
1 study · 2041 participants
GRADE not reported
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Specificity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, pooled specificity of radiographic detection for all (initial and advanced) occlusal caries was 84.8% (95% CI 77 to 90) (ungraded).
3 findings from 1 review
Specificity 84.8 [77, 90]
9 studies
GRADE not reported
Specificity 80.4 [72, 87]
11 studies
GRADE not reported
Specificity 77.8 [70, 84]
14 studies
GRADE not reported
Specificity for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, pooled specificity of radiographic detection for all (initial and advanced) proximal caries was 91.7% (95% CI 90 to 93) (ungraded).
3 findings from 1 review
Specificity 91.7 [90, 93]
34 studies
GRADE not reported
Specificity 90.0 [87, 92]
38 studies
GRADE not reported
Specificity 92.5 [91, 94]
31 studies
GRADE not reported
Secondary caries · People with permanent posterior teeth restored with class I or II direct restorations
No secondary caries was reported at 24 months in any of seven studies, so no meta-analysis was possible (ungraded).
2 findings from 1 review
Positive LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, the positive lr of radiographic detection for advanced occlusal caries was 5.87 (95% CI 4.3 to 8.0) (ungraded).
3 findings from 1 review
Positive LR 5.87 [4.3, 8.0]
36 studies
GRADE not reported
Positive LR 4.9 [3.7, 6.5]
44 studies
GRADE not reported
Positive LR 5.96 [3.7, 6.6]
38 studies
GRADE not reported
Death · Patients with severe malaria
The fixed-effect NMR reported a difference between artesunate and quinine at every displayed average age; no GRADE assessment was reported.
2 findings from 1 review
no estimate extracted
Studies not reported
GRADE not reported
no estimate extracted
Studies not reported
GRADE not reported
Advanced occlusal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical)
Pooled specificity for visual detection of advanced occlusal lesions was 0.849 (95% CI 0.82 to 0.89).
2 findings from 1 review
Specificity 84.9 [82, 89]
55 studies
GRADE not reported
Specificity 90.9 [88, 93]
94 studies
GRADE not reported
Positive LR for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the conventional (all-studies) meta-analysis, the positive lr of radiographic detection for all (initial and advanced) proximal caries was 4.3 (95% CI 3.4 to 5.5) (ungraded).
3 findings from 1 review
Positive LR 4.3 [3.4, 5.5]
38 studies
GRADE not reported
Positive LR 4.89 [3.9, 6.2]
34 studies
GRADE not reported
Positive LR 5.34 [4.2, 6.8]
31 studies
GRADE not reported
NPV for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the Egyptian public health clinic setting, the negative predictive value of visual detection for all (initial and advanced) occlusal caries was 97.4% at an assumed prevalence of 12.9% (ungraded).
2 findings from 1 review
NPV 97.4
51 studies
GRADE not reported
NPV 68.6
12 studies
GRADE not reported
Treatment success rate · Primary teeth with dentin caries lesions on occlusoproximal surfaces
The Hall technique ranked first for treatment success in the occlusoproximal-surface network (low certainty).
1 finding from 1 review
Marginal discoloration · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, marginal discoloration did not differ significantly (7 groups; p = 0.77; ungraded).
4 findings from 1 review
Show 1 more finding
Sensitivity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Egypt, pooled sensitivity of radiographic detection for advanced occlusal caries was 54.2% (95% CI 47 to 61) (ungraded).
3 findings from 1 review
Sensitivity 54.2 [47, 61]
38 studies
GRADE not reported
Sensitivity 52.3 [44, 60]
44 studies
GRADE not reported
Sensitivity 50.8 [43, 59]
36 studies
GRADE not reported
Caries increment, surface index D(M)FS · Children or adolescents
The illustrative network meta-regression estimated an SMD for caries increment for fluoride in varnish versus fluoride in dentifrice across randomization year; the review did not state whether the difference was significant and certainty was not graded.
1 finding from 1 review
Sensitivity for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the conventional (all-studies) meta-analysis, pooled sensitivity of radiographic detection for all (initial and advanced) proximal caries was 43.2% (95% CI 36 to 51) (ungraded).
3 findings from 1 review
Sensitivity 43.2 [36, 51]
38 studies
GRADE not reported
Sensitivity 40.2 [32, 48]
31 studies
GRADE not reported
Sensitivity 40.5 [33, 48]
34 studies
GRADE not reported
Dental caries · Adult participants in 25 meta-regression studies
The unadjusted meta-regression coefficient for older mean age was 4.324884.
2 findings from 1 review
Retention (restoration loss) · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, retention did not differ significantly between the composites (6 studies; ungraded).
2 findings from 1 review
Dental caries in permanent teeth · Children and adolescents with permanent dentition
No eligible studies examined prenatal tobacco exposure and caries in permanent dentition.
1 finding from 1 review
NPV for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the Egyptian public health clinic setting, the negative predictive value of radiographic detection for advanced occlusal caries was 89.3% at an assumed prevalence of 19.0% (ungraded).
2 findings from 1 review
NPV 89.3
38 studies
GRADE not reported
NPV 94.3
36 studies
GRADE not reported
Intervention not reported
Dental caries in permanent dentition (presence)
The intervention led to higher dental caries in permanent dentition (presence); GRADE not reported.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children or adolescents
The illustrative network meta-regression estimated an SMD for caries increment for fluoride in gel versus fluoride in rinse across randomization year; the review did not state whether the difference was significant and certainty was not graded.
1 finding from 1 review