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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Health related quality of life · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Adverse events · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Aqueous oxygen peroxide vs sterile water
Time to healing · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Aqueous oxygen peroxide vs sterile water
Number of wounds healed ‐ per protocol ‐ after 12 months of · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
RR 1.88 [1.1, 3.2]1 study · 34 participantsVery low
Self‐instruction and one‐to‐one counselling vs self‐instruction
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Education vs standard printed material
Proportion of participants developing a new pressure (12 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 3.57 [0.78, 16.38]1 study · 105 participantsVery low
Computerised feedback and one‐on‐one consultations vs no feedback
Time to occurrence of new ulcer · individuals with spinal cord injury
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Computerised feedback and one‐on‐one consultations vs no feedback
Proportion of participants developing a new ulcer · individuals with spinal cord injury
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Individualised pressure ulcer education and monthly structured telephone follow‐up vs standard pressure ulcer education and monthly mail or telephone follow‐up
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Individualised pressure ulcer education and monthly structured telephone follow‐up vs standard pressure ulcer education and monthly mail or telephone follow‐up
Proportion of participants developing a new ulcer (24 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 0.55 [0.23, 1.3]1 study · 31 participantsVery low
Standard pressure ulcer education and monthly mail or telephone follow‐up, vs standard pressure ulcer education and quarterly mail or telephone follow‐up,
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Standard pressure ulcer education and monthly mail or telephone follow‐up, vs standard pressure ulcer education and quarterly mail or telephone follow‐up,
Proportion of participants developing a new ulcer (24 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 0.61 [0.34, 1.08]1 study · 21 participantsVery low
Individualised pressure ulcer education and monthly structured telephone follow‐up vs standard pressure ulcer education and quarterly mail or telephone follow‐up,
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Individualised pressure ulcer education and monthly structured telephone follow‐up vs standard pressure ulcer education and quarterly mail or telephone follow‐up,
Proportion of participants developing a new ulcer (24 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 0.33 [0.17, 0.67]1 study · 31 participantsVery low
Spinal Cord Injury Navigator programme vs usual rehabilitation care/education
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Self‐instruction and one‐to‐one counselling vs self‐instruction
Proportion of participants developing a new ulcer (3 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 0.4 [0.14, 1.18]1 study · 92 participantsVery low
Spinal Cord Injury Navigator programme vs usual rehabilitation care/education
Proportion of participants developing a new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Multicomponent motivational interviewing/self‐management intervention with a multi component education intervention vs telephone‐based individual educational counselling plus group education
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Multicomponent motivational interviewing/self‐management intervention with a multi component education intervention vs telephone‐based individual educational counselling plus group education
Proportion of participants developing a new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Pressure ulcer prevention care bundle vs standard care
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Pressure ulcer prevention care bundle vs standard care
Proportion of participants developing a new ulcer (28 days) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
HR 0.58 [0.25, 1.33]1 study · 1598 participantsLow
Structured, patient‐centric pressure ulcer prevention education event vs standard unit education
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Structured, patient‐centric pressure ulcer prevention education event vs standard unit education
Proportion of participants developing a new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Carer self‐instruction and one‐to‐one counselling vs self‐instruction
Time to occurrence of a new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Carer self‐instruction and one‐to‐one counselling vs self‐instruction
Proportion of participants developing a new ulcer (12 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 2.05 [0.19, 21.7]1 study · 75 participantsVery low
Home‐based training vs usual care
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Home‐based training vs usual care
Proportion of participants developing a new ulcer (3 months) · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
RR 0.53 [0.27, 1.02]1 study · 70 participantsVery low
Enhanced educational intervention and structured follow‐up vs standard education alone
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Enhanced educational intervention and structured follow‐up vs standard education alone
Proportion of participants developing a new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Education vs standard printed material
Time to occurrence of new ulcer · s
Patient and lay carer education for preventing pressure ulceration in at‐risk populations (2021) · Cochrane
no estimate extractedNRNo studies
Psychological intervention vs standard care
Proportion of wounds completely healed at 3 months · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
RR 6.252 studies · 76 participantsVery low
Psychological intervention vs another psychological intervention
Number of foot ulcer recurrences · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
no estimate extractedNRNo studies
Psychological intervention vs standard care
Proportion of wounds completely healed at 6 weeks · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
RR 0.592 studies · 76 participantsVery low
Psychological intervention vs standard care
Time to complete wound healing · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
no estimate extractedNRNo studies
Psychological intervention vs standard care
Time to recurrence · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
no estimate extractedNRNo studies
Psychological intervention vs standard care
Number of foot ulcer recurrences at 1 year · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
RR 0.672 studies · 54 participantsVery low
Psychological intervention vs standard care
Number of foot ulcer recurrences at 6 months · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
RR 0.632 studies · 54 participantsVery low
Psychological intervention vs another psychological intervention
Proportion of wounds completely healed at 3 months · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
RR 2.331 study · 16 participantsVery low
Psychological intervention vs another psychological intervention
Time to complete wound healing · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
no estimate extracted2001 participantsUngraded
Psychological intervention vs another psychological intervention
Time to foot ulcer recurrence · adults with diabetes with current or previous foot ulceration
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Scar severity assessed by health professionals with VSS score from 0 to 15 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted2 studies · 31 participantsVery low
Silicone gel sheeting vs pressure garments
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs pressure garments
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs pressure garments
Pain assessed by VAS score from 0 to 10 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 48 participantsLow
Silicone gel sheeting vs pressure garments
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs pressure garments
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs pressure garments
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs pressure garments
CI: Confidence interval · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs silicone gel
Scar severity assessed by health professionals with VSS score from 0 to 14 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 20 participantsVery low
Silicone gel sheeting vs silicone gel
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies