Findings

What do systematic reviews say?

1,261 questions · 1,287 findings · 210 reviews

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No studies found 256 · 19.9%GRADE not reported 123 · 9.6%Very low 248 · 19.3%Low 403 · 31.3%Moderate 208 · 16.2%High 49 · 3.8%

Summary of findings ‐ nebulisers for delivering other aerosolised medications: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

Serum deposition Cmax · adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ nebulisers for delivering other aerosolised medications: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

Adverse events · adults with cystic fibrosis

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 15 participants
Very low

Summary of findings ‐ nebulisers for delivering other aerosolised medications: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

FEV1 · adults with cystic fibrosis

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 15 participants
Very low

Summary of findings ‐ nebulisers for delivering other aerosolised medications: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

Time to next exacerbation · adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ nebulisers for delivering other aerosolised medications: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

Participant satisfaction or preference · adults with cystic fibrosis

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 15 participants
Very low

Root canal medications and canal filling, splinting, extraction of teeth, or surgical removal of any relevant pathology vs Each other, placebo, or no treatment

Outcome not reported · Patients with single and multiple permanent teeth with evidence of any type of external root resorption irrespective of its aetiology,…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of external root resorption 2015 · Cochrane All outcomes
Any follow-up period
None of the studies fulfilled our inclusion criteria and therefore no data analysis was conducted. (Main results: no RCTs that met the inclusion criteria were identified; one ongoing study, NCT00423956, potentially…
0 studies
No studies found

Psychological interventions vs usual care, no intervention, or treatment with no psychological component

Behavioural outcome: medication use Multimodal/complexk, ATCS Plus versus usual care or enhanced usual care (plus information) · adolescents with asthma

1 finding from 1 review

Psychological interventions for asthma in children and adolescents 2024 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 822 participants
Very low

NSAIDs vs combined OCP

Requirement for additional medication · women with primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combined OCP vs placebo or no treatment

Requirement for additional medication · women with primary dysmenorrhoea

Combined OCP may leads to lower requirement for additional medication compared with placebo or no treatment (low certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 0.63 [0.4, 0.98]
2 studies · 163 participants
Low

Combined low‐dose OCP vs another combined low‐dose OCP

Requirement for additional medication · women with primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Simple educational intervention vs usual care

Residents with at least one psychotropic medication · older people in all long‐term care settings

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints for older people in all long‐term care settings 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1202 participants
Very low

Summary of findings table ‐ Providing information about the residents? fall risk vs usual care

Residents with at least one psychotropic medication ‐ not measured · older people in all long‐term care settings

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints for older people in all long‐term care settings 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Organisational interventions vs usual care

Residents with at least one psychotropic medication · older people in all long‐term care settings

Summary of findings table ‐ Organisational intervention showed no clear difference in residents with at least one psychotropic medication compared with usual care (moderate certainty).

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints for older people in all long‐term care settings 2023 · Cochrane Headline outcomes only
RR 1 [0.95, 1.06]
2 studies · 3452 participants
Moderate

Anti‐VEGF vs no anti‐VEGF

Proportion of participants with IOP ≤ 21 mmHg, with or without ocular hypotensive medications, 4 to 6 weeks · people with neovascular glaucoma

Anti‐VEGF may leads to higher proportion of participants with IOP ≤ 21 mmHg, with or without… compared with no anti‐VEGF (low certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor for neovascular glaucoma 2023 · Cochrane Headline outcomes only
RR 1.32 [1.1, 1.59]
1 study · 93 participants
Low

Pharmaceutical care vs usual care

Medication appropriateness · older people receiving polypharmacy

1 finding from 1 review

Interventions to improve the appropriate use of polypharmacy for older people 2023 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 947 participants
Very low

Pharmaceutical care vs usual care

The number of potentially inappropriate medications (PIMs) · older people receiving polypharmacy

1 finding from 1 review

Interventions to improve the appropriate use of polypharmacy for older people 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 2404 participants
Very low

Pharmaceutical care vs usual care

The proportion of patients with one or more potentially inappropriate medication (PIM) · older people receiving polypharmacy

It is very uncertain whether pharmaceutical care changes the proportion of patients with one or more potentially… compared with usual care (very low certainty).

1 finding from 1 review

Interventions to improve the appropriate use of polypharmacy for older people 2023 · Cochrane Headline outcomes only
RR 0.81 [0.68, 0.98]
13 studies · 4534 participants
Very low

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Irritability · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

1 finding from 1 review

Pharmacological intervention for irritability, aggression, and self‐injury in autism spectrum disorder (ASD) 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 400 participants
Low

Iridotomy vs no iridotomy

Mean number of antiglaucoma medications at 1‐year · people with primary angle‐closure suspect

The review found no eligible studies for this question.

1 finding from 1 review

Iridotomy to slow progression of visual field loss in angle‐closure glaucoma 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Culturally and literacy adapted medical instruction vs no health literacy intervention

Health literacy – Medication understanding Multiple measures used: Demonstration by means of correct dosage in dosing tray (0 to 5) Correct interpretation of label contents, 11 labels MUQ (score · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 478 participants
Low