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Evidence found and GRADE certainty

369 questions · 463 findings · 41 reviews · Oral Health

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No studies found 44 · 9.5%GRADE not reported 336 · 72.6%Very low 31 · 6.7%Low 26 · 5.6%Moderate 15 · 3.2%High 11 · 2.4%

Genetically predicted periodontitis vs Lower genetically predicted periodontitis liability

Postmenopausal osteoporosis with pathological fracture · European GWAS participants

The SVMR Weighted Median interval included the null.

3 findings from 1 review

Genetically predicted periodontitis vs Lower genetically predicted periodontitis liability

Postmenopausal osteoporosis with pathological fracture · Postmenopausal women (European ancestry)

Genetically predicted periodontitis had no causal effect on postmenopausal osteoporosis with pathological fracture (single-variable MR, OR 1.014).

2 findings from 1 review

Genetically predicted DMFS (dental caries) vs Reference (1-SD lower genetically predicted DMFS)

Femur fracture · European-ancestry adults

Genetically predicted dental caries (DMFS) had no significant causal effect on fracture of femur (multivariable MR, OR 1.069).

2 findings from 1 review

Out-of-pocket health expenditure vs Lower vs higher out-of-pocket expenditure categories

Oral health-related quality of life · people aged 60 years and older living in the community

Lower out-of-pocket health expenditure was associated with better OHRQoL (83.9, 95% CI 75.2 to 92.6 vs 67.5, 95% CI 58.5 to 76.5); the difference was statistically significant (ungraded).

2 findings from 1 review

Genetically predicted pulp and periapical diseases vs Without pulp and periapical diseases (lower genetic liability)

Lacunar stroke · European-ancestry adults

Genetically predicted pulp and periapical diseases were associated with modestly higher odds of lacunar stroke (OR 1.20); ungraded MR, FDR-adjusted P 0.033.

1 finding from 1 review

Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS

Forearm fracture · European GWAS participants

The SVMR Weighted Median interval included the null.

3 findings from 1 review

Thermoelastic copper NiTi (CuNiTi) arch wire vs Conventional (stabilised) NiTi arch wire

Time to next/working arch wire · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

Thermoelastic copper NiTi (CuNiTi) arch wire showed no clear difference in time to next/working arch wire compared with conventional NiTi arch wire; GRADE not reported.

1 finding from 1 review

Single-strand superelastic NiTi arch wire vs Coaxial superelastic NiTi arch wire

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

Single-strand superelastic NiTi arch wire probably leads to lower alignment rate compared with coaxial superelastic NiTi arch wire (moderate certainty).

1 finding from 1 review

Superelastic NiTi arch wire vs Thermoelastic NiTi arch wire

Root resorption · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

It is very uncertain whether superelastic NiTi arch wire changes root resorption (reduction in root length) compared with thermoelastic NiTi arch wire (very low certainty).

1 finding from 1 review

Higher mean patient age (per 1 year) vs Lower mean patient age (per 1-year decrement)

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, mean patient age was not significantly associated with space closure odds (OR 0.59 per year; not GRADE-rated).

1 finding from 1 review