Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

341 questions · 354 findings · 26 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 58 · 16.4%GRADE not reported 4 · 1.1%Very low 51 · 14.4%Low 133 · 37.6%Moderate 82 · 23.2%High 26 · 7.3%

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Absence of nausea and vomiting ( · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in absence of nausea and vomiting ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in withdrawal any reason ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Withdrawals due to adverse events · people with chemotherapy‐induced nausea and vomiting

It is very uncertain whether cannabinoid plus other anti‐emetic agent changes withdrawal due to adverse event ( compared with other anti‐emetic monotherapy (very low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Lack of efficacy withdrawal · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in withdrawal due to lack of efficacy ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review

Benefits and harms of CSF plus antibiotics vs antibiotics alone

Duration of grade IV neutropenia (lower values signify better outcomes) · people with chemotherapy‐induced febrile neutropenia

Benefits and harms of CSF plus antibiotics showed no clear difference in duration of grade IV neutropenia (lower values signify better… compared with antibiotics alone (low certainty).

1 finding from 1 review

Benefits and harms of CSF plus antibiotics vs antibiotics alone

Time to recovery from fever (lower values signify better outcomes) · people with chemotherapy‐induced febrile neutropenia

Benefits and harms of CSF plus antibiotics showed no clear difference in time to recovery from fever (lower values signify better outcomes) compared with antibiotics alone (low certainty).

1 finding from 1 review

Benefits and harms of CSF plus antibiotics vs antibiotics alone

Time to withdrawal from ATB (lower values signify better outcomes) · people with chemotherapy‐induced febrile neutropenia

Benefits and harms of CSF plus antibiotics showed no clear difference in time to withdrawal from ATB (lower values signify better outcomes) compared with antibiotics alone (low certainty).

1 finding from 1 review