What do systematic reviews say?

Intervention not reported

The intervention showed no clear difference in tobacco use (low certainty).

• Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
  OR 1.03 [0.32, 3.27]
  2 studies · 1549 participants
  Low

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

It is very uncertain whether provision of maize flour or maize flour products fortified with iron… changes anaemia (defined as haemoglobin (Hb) below WHO cut‐off, adjusted for… compared with unfortified maize flours or maize flour products (very low certainty).

• Fortification of maize flour with iron for controlling anaemia and iron deficiency in populations 2018 · Cochrane Headline outcomes only
  RR 0.9 [0.58, 1.4]
  2 studies · 1027 participants
  Very low

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

It is very uncertain whether provision of maize flour or maize flour products fortified with iron… changes iron deficiency (as defined by trialists, based on a biomarker of… compared with unfortified maize flours or maize flour products (very low certainty).

• Fortification of maize flour with iron for controlling anaemia and iron deficiency in populations 2018 · Cochrane Headline outcomes only
  RR 0.75 [0.49, 1.15]
  2 studies · 1102 participants
  Very low

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

• Fortification of maize flour with iron for controlling anaemia and iron deficiency in populations 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1144 participants
  Very low

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

• Fortification of maize flour with iron for controlling anaemia and iron deficiency in populations 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 584 participants
  Very low

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

The review found no eligible studies for this question.

• Fortification of maize flour with iron for controlling anaemia and iron deficiency in populations 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in intraoperative pain (reported dichotomous) (low certainty).

• Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults 2018 · Cochrane Headline outcomes only
  RR 0.83 [0.48, 1.42]
  4 studies · 289 participants
  Low

Intervention not reported

• Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 211 participants
  Low

Intervention not reported

• Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 122 participants
  Moderate

Intervention not reported

• Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 141 participants
  Moderate

Intervention not reported

• Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Medication reconciliation interventions vs usual care

It is very uncertain whether medication reconciliation interventions changes ≥ 1 medication discrepancy per participant (dichotomous) compared with standard care (very low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.53 [0.42, 0.67]
  20 studies · 4629 participants
  Very low

Medication reconciliation interventions vs usual care

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1963 participants
  Very low
• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.13 [0.01, 1.29]
  2 studies · 3595 participants
  Very low

Medication reconciliation interventions vs usual care

It is very uncertain whether medication reconciliation interventions changes PADEs compared with standard care (very low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.37 [0.09, 1.57]
  3 studies · 1253 participants
  Very low

Medication reconciliation interventions vs usual care

Medication reconciliation interventions showed no clear difference in ADEs compared with standard care (low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 1.09 [0.91, 1.3]
  4 studies · 1363 participants
  Low

Medication reconciliation interventions vs usual care

Medication reconciliation interventions showed no clear difference in unplanned rehospitalisation compared with standard care (moderate certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.72 [0.44, 1.18]
  5 studies · 1206 participants
  Moderate

Low tidal volume vs high tidal volume

Low tidal volume showed no clear difference in mortality compared with high tidal volume (low certainty).

• Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of… 2018 · Cochrane Headline outcomes only
  RR 0.8 [0.42, 1.53]
  12 studies · 1207 participants
  Low

Low tidal volume vs high tidal volume

Low tidal volume probably leads to lower pneumonia compared with high tidal volume (moderate certainty).

• Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of… 2018 · Cochrane Headline outcomes only
  RR 0.45 [0.25, 0.82]
  7 studies · 778 participants
  Moderate

Low tidal volume vs high tidal volume

Low tidal volume probably leads to lower need for postoperative non‐invasive ventilatory support compared with high tidal volume (moderate certainty).

• Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of… 2018 · Cochrane Headline outcomes only
  RR 0.31 [0.15, 0.64]
  3 studies · 506 participants
  Moderate