Cochrane · systematic review · CD010368
Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults
Rüschen, H, Aravinth, K, Bunce, C, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 33.3%Very low 0 · 0%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults
Population: adults (aged ≥ 18 years) undergoing ophthalmic surgery under local anaesthetic eye blocks.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraoperative pain (reported dichotomous) | RR 0.83 [0.48, 1.42] | 4 studies · 289 participants | Low Downgraded: inconsistency |
Intraoperative pain (reported continuous) | no estimate extracted | 3 studies · 211 participants | Low Downgraded: imprecision, inconsistency |
Incidence of harm | no estimate extracted | 0 studies · 0 participants | Ungraded |
Participant satisfaction | no estimate extracted | 2 studies · 122 participants | Moderate Downgraded: imprecision, inconsistency |
Surgical satisfaction | no estimate extracted | 3 studies · 141 participants | Moderate Downgraded: imprecision, inconsistency |
Economic outcomes or cost calculations | no estimate extracted | 0 studies · 0 participants | Ungraded |