Cochrane · systematic review · CD010791
Impact of medication reconciliation for improving transitions of care
Redmond, P, Grimes, TC, McDonnell, R, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Effective Practice and Organisation of CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Medication reconciliation interventions compared to standard care for all patients at a transition of care
Population: all patients (aged > 18 years) at a transition of care
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
≥ 1 medication discrepancy per participant (dichotomous) Medication reconciliation interventions vs standard care | RR 0.53 [0.42, 0.67] | 20 studies · 4629 participants | Very low Downgraded: inconsistency |
Number of medication discrepancies per participant (continuous) Medication reconciliation interventions vs standard care | no estimate extracted | 4 studies · 1963 participants | Very low Downgraded: inconsistency |
Discrepancies per participant medication Medication reconciliation interventions vs standard care | RR 0.13 [0.01, 1.29] | 2 studies · 3595 participants | Very low Downgraded: inconsistency |
PADEs Medication reconciliation interventions vs standard care | RR 0.37 [0.09, 1.57] | 3 studies · 1253 participants | Very low Downgraded: inconsistency |
ADEs Medication reconciliation interventions vs standard care | RR 1.09 [0.91, 1.3] | 4 studies · 1363 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Unplanned rehospitalisation Medication reconciliation interventions vs standard care | RR 0.72 [0.44, 1.18] | 5 studies · 1206 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Hospital usage (composite measure of ED, rehospitalisation) Medication reconciliation interventions vs standard care | RR 0.78 [0.5, 1.22] | 4 studies · 597 participants | Very low Downgraded: inconsistency |