Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

305 questions · 305 findings · 37 reviews

No studies found 75 · 24.6%GRADE not reported 22 · 7.2%Very low 57 · 18.7%Low 97 · 31.8%Moderate 46 · 15.1%High 8 · 2.6%

Vaginal PGE₂ vs placebo or expectant management

Uterine hyperstimulation (fetal heart rate changes unclear) · patients with induction of labour at term

Vaginal PGE₂ showed no clear difference in uterine hyperstimulation (fetal heart rate changes unclear) compared with placebo or expectant management (low certainty).

1 finding from 1 review

Double‐balloon catheter vs vaginal PGE2

Caesarean section · women with a previous caesarean section (subgroup of all women in the study) with intact fetal membranes, cephalic position and…

It is very uncertain whether double‐balloon catheter changes caesarean section compared with vaginal PGE2 (very low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Caesarean section · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in caesarean section compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious neonatal morbidity or perinatal death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious neonatal morbidity/perinatal death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious maternal morbidity or death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious maternal morbidity or death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review