Question · asked by 1 review
Vaginal PGE2 vs intravenous (IV) oxytocin: Serious maternal morbidity or death
- Population
- women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia, singleton in cephalic presentation, GA ≥ 37 weeks, BS < 9, no cephalopelvic disproportion anticipated
- Intervention
- Vaginal PGE2
- Comparison
- intravenous (IV) oxytocin
- Outcome
- Serious maternal morbidity or death
Vaginal PGE2 showed no clear difference in serious maternal morbidity or death compared with intravenous (IV) oxytocin (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Vaginal PGE2 vs intravenous (IV) oxytocin Serious maternal morbidity or death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or… Vaginal PGE2 showed no clear difference in serious maternal morbidity or death compared with intravenous (IV) oxytocin (low certainty). Methods of term labour induction for women with a previous caesarean section (2017) · Cochrane Headline outcomes only | RR 3 [0.13, 69.7] | 1 study · 42 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.