Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

305 questions · 305 findings · 37 reviews

No studies found 75 · 24.6%GRADE not reported 22 · 7.2%Very low 57 · 18.7%Low 97 · 31.8%Moderate 46 · 15.1%High 8 · 2.6%

Labour induction vs expectant management

Severe perineal tears (3rd degree or higher, as defined by trialists) · pregnant women at or beyond 37 weeks gestation

Labour induction showed no clear difference in perineal trauma (severe perineal tear) compared with expectant management (maternal outcomes) (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no antibiotic

Probable early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term

Any antibiotic showed no clear difference in probable early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no antibiotic

Probable early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term

It is very uncertain whether any antibiotic changes probable early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no antibiotic

Definite early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term

Any antibiotic showed no clear difference in definite early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no antibiotic

Definite early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term

It is very uncertain whether any antibiotic changes definite early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no antibiotic

Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term

Any antibiotic showed no clear difference in maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no antibiotic

Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term

It is very uncertain whether any antibiotic changes maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).

1 finding from 1 review