Findings

What do systematic reviews say?

319 questions · 323 findings · 28 reviews · Eyes and Vision

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No studies found 85 · 26.3%GRADE not reported 10 · 3.1%Very low 80 · 24.8%Low 103 · 31.9%Moderate 41 · 12.7%High 4 · 1.2%

Intracameral mydriatics vs depot delivery systems

Adverse events · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical mydriatics vs intracameral mydriatics

Mean pupillary diameter—at the end of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 799 participants
Low

Topical mydriatics vs intracameral mydriatics

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 817 participants
Low

Topical mydriatics vs intracameral mydriatics

AE: posterior capsule rupture · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: posterior capsule rupture compared with intracameral mydriatics (low certainty).

2 findings from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low
Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Visual acuity · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in head posture ‐ not reported · infantile nystagmus syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in visual recognition times ‐ not reported · infantile nystagmus syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in proportion of participants with adverse effects with a probable causal link to the treatment · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in quality of life · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Intervention not reported

Change in BCVA from baseline to 6‐month · People with lamellar macular holes

1 finding from 1 review

Surgical interventions for lamellar macular holes 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Intervention not reported

Change in metamorphopsia from baseline to 6‐month · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for lamellar macular holes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Change in anatomical outcomes (CRT) from baseline to 6‐month · People with lamellar macular holes

1 finding from 1 review

Surgical interventions for lamellar macular holes 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Intervention not reported

Retinal sensitivity · People with lamellar macular holes

1 finding from 1 review

Surgical interventions for lamellar macular holes 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Intervention not reported

Vision‐related quality of life · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for lamellar macular holes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse outcomes · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for lamellar macular holes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any prophylaxis vs no prophylaxis

Blindness · newborn children

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any prophylaxis vs no prophylaxis

Any adverse visual outcome · newborn children

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any prophylaxis vs no prophylaxis

Gonococcal conjunctivitis · newborn children

It is very uncertain whether any prophylaxis changes gonococcal conjunctivitis compared with no prophylaxis (very low certainty).

1 finding from 1 review

Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
RR 0.79 [0.24, 2.65]
3 studies · 8229 participants
Very low

Any prophylaxis vs no prophylaxis

Chlamydial conjunctivitis · newborn children

Any prophylaxis showed no clear difference in chlamydial conjunctivitis compared with no prophylaxis (low certainty).

1 finding from 1 review

Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
RR 0.96 [0.57, 1.61]
2 studies · 4874 participants
Low

Any prophylaxis vs no prophylaxis

Bacterial conjunctivitis · newborn children

Any prophylaxis showed no clear difference in bacterial conjunctivitis compared with no prophylaxis (low certainty).

1 finding from 1 review

Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
RR 0.84 [0.37, 1.93]
2 studies · 3685 participants
Low