Cochrane · systematic review · CD001862
Interventions for preventing ophthalmia neonatorum
Kapoor, VS, Evans, JR, Vedula, SS · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
2
Included studies
NR
No studies 2 · 25%Ungraded 0 · 0%Very low 3 · 37.5%Low 2 · 25%Moderate 1 · 12.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Any prophylaxis compared to no prophylaxis for the prevention of ophthalmia neonatorum in newborn children
Population: newborn children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Blindness (visual acuity less than 20/200) Any prophylaxis vs no prophylaxis | no estimate extracted | NR | No studies |
Any adverse visual outcome Any prophylaxis vs no prophylaxis | no estimate extracted | NR | No studies |
Gonococcal conjunctivitis Any prophylaxis vs no prophylaxis | RR 0.79 [0.24, 2.65] | 3 studies · 8229 participants | Very low Downgraded: risk of bias, imprecision |
Chlamydial conjunctivitis Any prophylaxis vs no prophylaxis | RR 0.96 [0.57, 1.61] | 2 studies · 4874 participants | Low Downgraded: risk of bias |
Bacterial conjunctivitis Any prophylaxis vs no prophylaxis | RR 0.84 [0.37, 1.93] | 2 studies · 3685 participants | Low Downgraded: risk of bias |
Any conjunctivitis of any aetiology Any prophylaxis vs no prophylaxis | RR 0.65 [0.54, 0.78] | 8 studies · 9666 participants | Moderate Downgraded: risk of bias |
Conjunctivitis of unknown aetiology Any prophylaxis vs no prophylaxis | RR 1.75 [0.37, 8.28] | 1 study · 330 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects Any prophylaxis vs no prophylaxis | OR 0.93 | 1993 participants | Very low Downgraded: risk of bias, imprecision |