Findings

What do systematic reviews say?

2,191 questions · 2,354 findings · 362 reviews

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No studies found 323 · 13.7%GRADE not reported 382 · 16.2%Very low 555 · 23.6%Low 597 · 25.4%Moderate 345 · 14.7%High 152 · 6.5%

Intervention not reported

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
51 studies · 8064 participants
High

Intervention not reported

Withdrawal due to adverse effects · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 3698 participants
Very low

Mask vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

Face mask may leads to lower treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (low certainty).

1 finding from 1 review

Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age 2014 · Cochrane Headline outcomes only
OR 0.2 [0.05, 0.88]
1 study · 80 participants
Low

Head box vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

It is very uncertain whether head box changes treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (very low certainty).

1 finding from 1 review

Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age 2014 · Cochrane Headline outcomes only
OR 0.4 [0.13, 1.12]
1 study · 80 participants
Very low

Intervention not reported

Decrease in systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Decrease in diastolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Decrease in heart rate · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 256 participants
Very low

Intervention not reported

Decrease in pulse pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Withdrawal due to adverse effect · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Very low

Nonselective beta‐blockers vs placebo

SBP (mmHg) · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Low

Nonselective beta‐blockers vs placebo

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Low

Nonselective beta‐blockers vs placebo

Heart rate · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 864 participants
Low

Nonselective beta‐blockers vs placebo

Pulse pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Very low

Nonselective beta‐blockers vs placebo

Withdrawals due to adverse events · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 729 participants
Low

Dihydropyridine calcium channel blockers vs placebo

Variation in the decrease in 24‐hour ambulatory hourly SBP (at 3 to 12 weeks) · adults with primary hypertension

1 finding from 1 review

Time course for blood pressure lowering of dihydropyridine calcium channel blockers 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 2768 participants
Moderate

Dihydropyridine calcium channel blockers vs placebo

Variation in the decrease in 24‐hour ambulatory hourly DBP (at 3 to 12 weeks) · adults with primary hypertension

1 finding from 1 review

Time course for blood pressure lowering of dihydropyridine calcium channel blockers 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 2768 participants
Moderate

Intervention not reported

LDL‐Cholesterol rosuvastatin 2.5 mg/day · participantswith normal or abnormal lipid profiles

1 finding from 1 review

Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 450 participants
Low

Intervention not reported

LDL‐Cholesterol rosuvastatin 5 mg/day · participantswith normal or abnormal lipid profiles

1 finding from 1 review

Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
no estimate extracted
25 studies · 2602 participants
High

Intervention not reported

LDL‐Cholesterol rosuvastatin 10 mg/day · participantswith normal or abnormal lipid profiles

1 finding from 1 review

Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
no estimate extracted
74 studies · 9855 participants
High

Intervention not reported

LDL‐Cholesterol rosuvastatin 20 mg/day · participantswith normal or abnormal lipid profiles

1 finding from 1 review

Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 3675 participants
High