Cochrane · systematic review · CD005975

Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age

Rojas‐Reyes, MX, Granados Rugeles, C, Charry‐Anzola, LP · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 25%Low 6 · 75%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Nasal prongs versus nasopharyngeal catheter for lower respiratory tract infections

Population: children with acute lower respiratory tract infections
6 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment failure Failure to achieve adequate oxygenation (SaO2)
Nasal prongs vs nasopharyngeal catheter
RR 0.97 [0.52, 1.8]3 studies · 399 participantsVery low
Downgraded: risk of bias, imprecision
Oxygen required in the first 24 hours Litres per minute (L/min)
Nasal prongs vs nasopharyngeal catheter
no estimate extracted3 studies · 338 participantsLow
Downgraded: risk of bias, imprecision
Nasal obstruction/severe mucus production
Nasal prongs vs nasopharyngeal catheter
RR 0.2 [0.09, 0.44]3 studies · 338 participantsLow
Downgraded: risk of bias, imprecision
Nose ulceration or bleeding
Nasal prongs vs nasopharyngeal catheter
RR 0.43 [0.18, 1.02]3 studies · 338 participantsLow
Downgraded: risk of bias, imprecision
Fighting/discomfort in the first 24 hours
Nasal prongs vs nasopharyngeal catheter
RR 0.77 [0.46, 1.28]2 studies · 239 participantsLow
Downgraded: imprecision
Death during treatment
Nasal prongs vs nasopharyngeal catheter
RR 0.64 [0.35, 1.15]3 studies · 338 participantsLow
Downgraded: imprecision

Face mask compared to nasopharyngeal catheter for severe acute LRTIs in children

Population: children with severe acute LRTIs
1 question
OutcomeEffectEvidenceStatus / GRADE
Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg)
Face mask vs nasopharyngeal catheter
OR 0.2 [0.05, 0.88]1 study · 80 participantsLow

Head box compared to nasopharyngeal catheter for severe acute LRTIs in children

Population: children with severe acute LRTIs
1 question
OutcomeEffectEvidenceStatus / GRADE
Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg)
Head box vs nasopharyngeal catheter
OR 0.4 [0.13, 1.12]1 study · 80 participantsVery low