Findings

What do systematic reviews say?

3,801 questions · 4,079 findings · 473 reviews

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No studies found 669 · 16.4%GRADE not reported 852 · 20.9%Very low 738 · 18.1%Low 903 · 22.1%Moderate 716 · 17.6%High 201 · 4.9%

Aspirin vs placebo

Major bleedinga · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin leads to higher major bleedinga compared with placebo (high certainty).

1 finding from 1 review

Antiplatelet agents and anticoagulants for hypertension 2022 · Cochrane Headline outcomes only
OR 1.77 [1.34, 2.32]
2 studies · 21330 participants
High

Aspirin vs placebo

Cardiovascular events · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin may leads to lower all cardiovascular events compared with placebo (low certainty).

1 finding from 1 review

Antiplatelet agents and anticoagulants for hypertension 2022 · Cochrane Headline outcomes only
OR 0.86 [0.77, 0.96]
3 studies · 35794 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Fetal immobilisation score at 40 minutes (Degree of fetal immobilisation as defined by trial authors) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Fetal movements ‐ gross body and limb (Degree of fetal immobilisation as defined by trial authors) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
RR 2.88 [1.6, 5.15]
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Maternal respiratory rate (Maternal respiratory depression as defined by trial authors or measured using intraoperative maternal arterial oxygen saturation and maternal respiratory rate) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
RR 0.09 [0.01, 0.65]
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Perinatal mortality · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Remifentanil vs diazepam

Time taken to perform procedure · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Drug use · People entitled to the drug insurance scheme (elderly and/or poor population)

1 finding from 1 review

Pharmaceutical policies: effects of regulating drug insurance schemes 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Drug expenditure · People entitled to the drug insurance scheme (elderly and/or poor population)

1 finding from 1 review

Pharmaceutical policies: effects of regulating drug insurance schemes 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Healthcare utilisation · People entitled to the drug insurance scheme (elderly and/or poor population)

1 finding from 1 review

Pharmaceutical policies: effects of regulating drug insurance schemes 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Health outcomes · People entitled to the drug insurance scheme (elderly and/or poor population)

1 finding from 1 review

Pharmaceutical policies: effects of regulating drug insurance schemes 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Systemic therapy vs control

Grip strength ‐ Vitamin D · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

Summary of findings table ‐ Systemic therapy vs control

Effect on breast cancer‐specific quality of life (BCS‐QoL) · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 147 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Health‐related quality of life (HRQoL) · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 208 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Safety of systemic therapies for the treatment of AIMSS · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1250 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Change in pain from baseline to end of intervention · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1099 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Change in stiffness from baseline to end of intervention · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 295 participants
Very low

Intervention not reported

Specimen · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

The review found no eligible studies for this question.

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found