Findings

What do systematic reviews say?

3,703 questions · 3,824 findings · 858 reviews

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No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

NSAIDs vs placebo or no treatment

RRT within 30 days of surgery · adults with normal kidney function undergoing surgery

It is very uncertain whether nonsteroidal anti‐inflammatory drugs (NSAIDs) changes RRT within 30 days of surgery compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Effects of peri‐operative nonsteroidal anti‐inflammatory drugs on post‐operative kidney function for adults with… 2018 · Cochrane Headline outcomes only
RR 1.57 [0.49, 5.07]
2 studies · 7056 participants
Very low

Intervention not reported

Postoperative delirium (POD) within 7 days (As assessed by any method such as the Mini‐Mental State Examination (MMSE) and Confusion Assessment Method (CAM) in the first week after operation) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations

The intervention probably leads to lower postoperative delirium (POD) within 7 days (As assessed by any… (moderate certainty).

1 finding from 1 review

Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and… 2018 · Cochrane Headline outcomes only
RR 0.71 [0.59, 0.85]
3 studies · 2197 participants
Moderate

Intervention not reported

Postoperative length of stay (days) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations

1 finding from 1 review

Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1155 participants
Low

Intervention not reported

Gabapentin up to 900 mg/day) versus baclofen (up to 30 mg/day). · people with acquired nystagmus

1 finding from 1 review

Interventions for eye movement disorders due to acquired brain injury 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Sliding scale insulin vs basal‐bolus insulin

Length of hospital stay · non‐critically ill hospitalised adults with diabetes mellitus

1 finding from 1 review

Sliding scale insulin for non‐critically ill hospitalised adults with diabetes mellitus 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 717 participants
Very low

Cyclamen europaeum vs placebo

Proportion of participants with resolution or improvement of symptoms up to 30 days · adults with acute sinusitis

The review found no eligible studies for this question.

1 finding from 1 review

Cyclamen europaeum extract for acute sinusitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mesh vs non‐mesh repair

Mortality (within 30 days post‐surgery) · adults undergoing inguinal and femoral hernia repair

The review found no eligible studies for this question.

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mesh vs non‐mesh repair

Length of postoperative hospital stay · adults undergoing inguinal and femoral hernia repair

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 2966 participants
Low

Mesh vs non‐mesh repair

Time to return to full ADLs (days) · adults undergoing inguinal and femoral hernia repair

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 3183 participants
Low

Summary of findings for additional food items between meals vs usual care

Food and fluid intake, measured by calories consumed in total per day (kcal, · people with dementia

1 finding from 1 review

Environmental and behavioural modifications for improving food and fluid intake in people with dementia 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Botulinum toxin type A vs placebo

Number of migraine days per month: chronic migraine only · adults with migraine

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1497 participants
Low

Botulinum toxin type A vs placebo

Number of migraine days per month · adults with migraine

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1915 participants
Very low

Botulinum toxin type A vs placebo

Number of headache days per month: chronic migraine only · adults with migraine

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1384 participants
High

Botulinum toxin type A vs other established prophylactic agent

Number of migraine days per month: chronic migraine only · adults with migraine

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Botulinum toxin type A vs other established prophylactic agent

Headache (frequency) · adults with migraine

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy

Early morbidity (any complication during the first 30 to 60 days following surgery)

It is very uncertain whether laparoscopic retroperitoneal adrenalectomy changes early morbidity (any complication during the first 30 to 60 days… compared with laparoscopic transperitoneal adrenalectomy (very low certainty).

1 finding from 1 review

Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults 2018 · Cochrane Headline outcomes only
RR 0.56 [0.27, 1.16]
5 studies · 244 participants
Very low

Absorbable vs non‐absorbable sutures

Postoperative pain: early pain (10 days postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)

2 findings from 1 review

Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 137 participants
Very low
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low

Oropharyngeal colostrum (OPC) vs No treatment or saline or water

Time to achieve full enteral feeding (days) · preterm infants

1 finding from 1 review

Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 335 participants
Very low

Oropharyngeal colostrum (OPC) vs No treatment or saline or water

Length of hospital stay · preterm infants

1 finding from 1 review

Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 293 participants
Very low

Mirtazapine adjunct vs placebo adjunct

Service utilisation outcomes: hospital admission or days in hospital · schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Mirtazapine adjunct for people with schizophrenia 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found