Cochrane · systematic review · CD011296
Sliding scale insulin for non‐critically ill hospitalised adults with diabetes mellitus
Colunga‐Lozano, LE, Gonzalez Torres, FJ, Delgado‐Figueroa, N, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 3 · 42.9%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Sliding scale insulin compared to basal‐bolus insulin for non‐critically ill hospitalised adults with diabetes mellitus
Population: non‐critically ill hospitalised adults with diabetes mellitus
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality (N) Sliding scale insulin vs basal‐bolus insulin | Peto OR 0.5 [0.05, 4.85] | 4 studies · 602 participants | Low Downgraded: imprecision |
Diabetes‐related morbidity Sliding scale insulin vs basal‐bolus insulin | no estimate extracted | NR | No studies |
Severe hypoglycaemic episodes (N) Sliding scale insulin vs basal‐bolus insulin | RR 0.22 [0.05, 1] | 5 studies · 667 participants | Very low Downgraded: risk of bias, imprecision |
Length of hospital stay (days) Sliding scale insulin vs basal‐bolus insulin | no estimate extracted | 6 studies · 717 participants | Very low Downgraded: imprecision, inconsistency |
Adverse events other than hypoglycaemic episodes (postoperative complications, mainly infectious) (N) Sliding scale insulin vs basal‐bolus insulin | RR 1.16 [0.25, 5.37] | 3 studies · 481 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Mean glucose level (mg/dL (mmol/L)) Sliding scale insulin vs basal‐bolus insulin | no estimate extracted | 6 studies · 717 participants | Low Downgraded: risk of bias, imprecision |
Socioeconomic effects Sliding scale insulin vs basal‐bolus insulin | no estimate extracted | NR | No studies |