Doxycycline+Rifampicin vs Doxycycline+Streptomycin
Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with doxycycline+Streptomycin (low certainty).
- RR 1.38 [0.99, 1.92]5 studies · 473 participantsLow
Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with doxycycline+Streptomycin (low certainty).
Doxycycline+Rifampicin showed no clear difference in total treatment failure compared with quinolones+Rifampicin (moderate certainty).
Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with quinolones+Rifampicin (low certainty).
Doxycycline+Streptomycin showed no clear difference in total treatment failure compared with doxycycline+Gentamycin (low certainty).
It is very uncertain whether doxycycline+Streptomycin changes minor adverse drug reactions compared with doxycycline+Gentamycin (very low certainty).
Short course showed no clear difference in hospitalization compared with long course treatment (low certainty).
Short course probably leads to higher bacteriuria compared with long course treatment (moderate certainty).
Short course showed no clear difference in fever compared with long course treatment (moderate certainty).
Short course showed no clear difference in UTI compared with long course treatment (moderate certainty).
The intervention led to higher treatment failure at 1 month or less; GRADE not reported.
The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.
The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.
The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.
The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.
The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.
The intervention showed no clear difference in treatment failure at 90 days; GRADE not reported.
The intervention showed no clear difference in treatment failure at 30 to 45 days; GRADE not reported.