Cochrane · systematic review · CD001095
Short‐course antibiotics for acute otitis media
Kozyrskyj, AL, Klassen, TP, Moffatt, M, et al. · Cochrane Database of Systematic Reviews · 2010 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
0
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 11 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Short‐acting antibiotic > 48 hours short‐term treatment for acute otitis media
Population: patients with acute otitis media
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Treatment failure at 1 month or less | OR 1.34 [1.15, 1.55] | 16 studies · 5093 participants | Ungraded |
Treatment failure at 8 to 19 days | OR 1.37 [1.15, 1.64] | 11 studies · 3932 participants | Ungraded |
Treatment failure at 20 to 30 days | OR 1.16 [0.94, 1.42] | 9 studies · 2476 participants | Ungraded |
Treatment failure at 3 months or less | OR 1.18 [0.98, 1.41] | 7 studies · 2068 participants | Ungraded |
Treatment failure at 90 days | OR 1.16 [0.65, 2.06] | 2 studies · 207 participants | Ungraded |
Treatment failure at 30 to 45 days | OR 1.18 [0.97, 1.43] | 5 studies · 1861 participants | Ungraded |
Ceftriaxone for acute otitis media
Population: patients with acute otitis media
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Treatment failure at 1 month or less | OR 1.07 [0.86, 1.33] | 8 studies · 1709 participants | Ungraded |
Treatment failure at 3 months or less | OR 0.89 [0.66, 1.21] | 3 studies · 701 participants | Ungraded |
Azithromycin 3 to 5 days short‐term treatment for acute otitis media
Population: patients with acute otitis media
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Treatment failure at 1 month or less | OR 1.02 [0.87, 1.2] | 19 studies · 4354 participants | Ungraded |
Treatment failure at 8 to 19 days | OR 1.27 [1.04, 1.55] | 18 studies · 4347 participants | Ungraded |
Treatment failure at 20 to 30 days | OR 0.98 [0.82, 1.17] | 11 studies · 2708 participants | Ungraded |