Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

BRIEF FAMILY INTERVENTION vs usual care

Global state: relapse ‐ medium term ‐ not measured · patients with schizophrenia

BRIEF FAMILY INTERVENTION showed no clear difference in global state ‐ relapse ‐ medium to long term relapse rates (clinical… compared with STANDARD CARE (low certainty).

1 finding from 1 review

INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT + STANDARD CARE vs usual care

Compliance with medication · patients with treatment compliance for people with serious mental illness

INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT… showed no clear difference in compliance with medication: Would stop taking medication Morisky… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT + STANDARD CARE vs usual care

Acceptability (of intervention): Leaving the studies early – any reason Loss to · patients with treatment compliance for people with serious mental illness

INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT… showed no clear difference in acceptability (of intervention): Leaving the studies early – any… compared with STANDARD CARE (low certainty).

1 finding from 1 review

TRIFLUOPERAZINE vs placebo

Global state ‐ clinical improvement ‐ medium term As defined by each study · patients with schizophrenia

TRIFLUOPERAZINE may leads to higher global state ‐ clinical improvement ‐ medium term As defined by each… compared with PLACEBO (low certainty).

1 finding from 1 review