Nausea · women having medical abortion before 14 weeks' gestation
Summary of findings table ‐ Ibuprofen 800 mg showed no clear difference in gastrointestinal side effects (nausea) compared with placebo (low certainty).
1 finding from 1 review
Vomiting · women having medical abortion before 14 weeks' gestation
Summary of findings table ‐ Ibuprofen 800 mg may leads to lower gastrointestinal side effects (vomiting) compared with placebo (low certainty).
1 finding from 1 review
Gastrointestinal side effects (diarrhoea) ‐ not reported · women having medical abortion before 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Complete abortion rate · women having medical abortion before 14 weeks' gestation
Summary of findings table ‐ Ibuprofen 800 mg showed no clear difference in complete abortion rate compared with placebo (low certainty).
1 finding from 1 review
Induction to expulsion interval ‐ not reported · women having medical abortion before 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Unscheduled contact with care ‐ not reported · women having medical abortion before 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction with analgesia ‐ not reported · women having medical abortion before 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction with abortion care overall ‐ not reported · women having medical abortion before 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Median (mean) time to use of rescue medication · health problem or population
1 finding from 1 review
Number of participants reporting an adverse event · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants reporting or experiencing any adverse event compared with active comparator (acetaminophen) (very low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · health problem or population
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low
At least 50% reduction in pain · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants with at least 50% pain relief at 4 hours compared with active comparator (acetaminophen) (very low certainty).
2 findings from 1 review
Number of participants using rescue medication over 4 to 6 hours postinterventions · health problem or population
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Specific behaviour ‐ agitation
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Response for agitation ‐ as defined by authors of RCTs ‐ 1303 persons in 4 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Psychosis ‐ presented in units of NPI‐NH P (higher is worse)d ‐ 3364 persons in 12 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Response for psychosis ‐ as defined by authors of RCTs ‐ 1958 persons in 7 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms
1 finding from 1 review
no estimate extracted
Studies not reported
High
Somnolence
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Death ‐ 5032 persons in 17 RCTs of 3 to 12 weeks ___________________________________________
1 finding from 1 review
no estimate extracted
Studies not reported
Low