Findings

What do systematic reviews say?

2,038 questions · 2,118 findings · 339 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 323 · 15.3%GRADE not reported 166 · 7.8%Very low 552 · 26.1%Low 592 · 28%Moderate 340 · 16.1%High 145 · 6.8%

Intervention not reported

Incidence of adverse events ‐ co‐trimoxazole prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in incidence of adverse events ‐ co‐trimoxazole prophylaxis only (moderate certainty).

1 finding from 1 review

Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
RR 0.9 [0.47, 1.73]
1 study · 534 participants
Moderate

Intervention not reported

Incidence of adverse events ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in incidence of adverse events ‐ isoniazid prophylaxis only (moderate certainty).

1 finding from 1 review

Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
RR 1.09 [0.55, 2.19]
2 studies · 810 participants
Moderate

Intervention not reported

Incidence of Pseudomonas infection in children with cystic fibrosis ‐ ciprofloxacin prophylaxis only · children with cystic fibrosis aged 12 years and under

The intervention showed no clear difference in incidence of Pseudomonas infection in children with cystic fibrosis… (moderate certainty).

1 finding from 1 review

Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
RR 0.76 [0.44, 1.31]
2 studies · 106 participants
Moderate

Intervention not reported

Mean FEV1 % predicted · children with cystic fibrosis aged 12 years and under

1 finding from 1 review

Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 418 participants
Moderate

Intervention not reported

Systolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 663 participants
Moderate

Intervention not reported

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 662 participants
Moderate

Intervention not reported

Systolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
47 studies · 7733 participants
High

Intervention not reported

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
51 studies · 8064 participants
High

Intervention not reported

Withdrawal due to adverse effects · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 3698 participants
Very low

Mask vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

Face mask may leads to lower treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (low certainty).

1 finding from 1 review

Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age 2014 · Cochrane Headline outcomes only
OR 0.2 [0.05, 0.88]
1 study · 80 participants
Low

Head box vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

It is very uncertain whether head box changes treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (very low certainty).

1 finding from 1 review

Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age 2014 · Cochrane Headline outcomes only
OR 0.4 [0.13, 1.12]
1 study · 80 participants
Very low

Intervention not reported

Decrease in systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Decrease in diastolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Decrease in heart rate · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 256 participants
Very low

Intervention not reported

Decrease in pulse pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Withdrawal due to adverse effect · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Very low

Nonselective beta‐blockers vs placebo

SBP (mmHg) · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Low

Nonselective beta‐blockers vs placebo

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Low

Nonselective beta‐blockers vs placebo

Heart rate · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 864 participants
Low

Nonselective beta‐blockers vs placebo

Pulse pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Very low