Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

764 questions · 795 findings · 110 reviews

No studies found 202 · 25.4%GRADE not reported 100 · 12.6%Very low 225 · 28.3%Low 155 · 19.5%Moderate 85 · 10.7%High 28 · 3.5%

Face‐down positioning vs other positioning

Quality of life assessments at 3 months or later (higher is favored) · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes quality of life assessments at 3 months or later (higher is favored) compared with other positioning (very low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Intervention not reported

Pain intensity measured on CHQ (0‐100; 0 = worse pain), and VAS (0 to 100; 0 = no pain) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

Intervention not reported

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Stroke · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes any stroke (fatal or non‐fatal; contralateral, ipsilateral or… compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Perioperative ipsilateral stroke (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes ipsilateral stroke (fatal or non‐fatal; haemorrhage or infarct)… compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Long‐term any stroke · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes any stroke (fatal or non‐fatal; contralateral, ipsilateral or… compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Long‐term ipsilateral stroke · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes ipsilateral stroke (fatal or non‐fatal; haemorrhage or infarct)… compared with primary closure (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D1: Total deaths (after randomisation) up to mid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D1: Total deaths (after randomisation) up to mid‐ to later childhood compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D2: Neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D2: Neurocognitive impairment atmid‐ to later childhood compared with single course (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D3: Survival free of neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D3: Survival free of neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D4: Survival free of major neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D4: Survival free of major neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability at 12 months or later · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review