Cochrane · systematic review · CD000160
Patch angioplasty versus primary closure for carotid endarterectomy
Orrapin, S, Benyakorn, T, Siribumrungwong, B, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Main comparison of patch angioplasty versus primary closure
Population: people undergoing carotid endarterectomy, whether initial indication for endarterectomy was symptomatic or asymptomatic carotid disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Any stroke (fatal or non‐fatal; contralateral, ipsilateral or brainstem; haemorrhage or infarct) within 30 days of operation Main comparison of patch angioplasty vs primary closure | OR 0.57 [0.31, 1.03] | 8 studies · 1769 participants | Very low Downgraded: risk of bias, imprecision |
Ipsilateral stroke (fatal or non‐fatal; haemorrhage or infarct) within 30 days of operation Main comparison of patch angioplasty vs primary closure | OR 0.31 [0.15, 0.63] | 7 studies · 1201 participants | Very low Downgraded: risk of bias, imprecision |
Occlusion of the operated artery within 30 days of operation Main comparison of patch angioplasty vs primary closure | OR 0.18 [0.08, 0.41] | 7 studies · 1435 participants | Low Downgraded: risk of bias, imprecision |
Any stroke (fatal or non‐fatal; contralateral, ipsilateral or brainstem; haemorrhage or infarct) during long‐term Main comparison of patch angioplasty vs primary closure | OR 0.49 [0.27, 0.9] | 7 studies · 1332 participants | Very low Downgraded: risk of bias, imprecision |
Ipsilateral stroke (fatal or non‐fatal; haemorrhage or infarct) during long‐term Main comparison of patch angioplasty vs primary closure | OR 0.32 [0.16, 0.63] | 6 studies · 1141 participants | Very low Downgraded: risk of bias, imprecision |
Any stroke or death during long‐term Main comparison of patch angioplasty vs primary closure | OR 0.59 [0.42, 0.84] | 6 studies · 1019 participants | Very low Downgraded: risk of bias, imprecision |
Restenosis (> 50%) or occlusion of operated artery during long‐term Main comparison of patch angioplasty vs primary closure | OR 0.24 [0.17, 0.34] | 8 studies · 1719 participants | Low Downgraded: risk of bias, imprecision, inconsistency |