Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

45 questions · 47 findings · 28 reviews · Headline outcomes only

No studies found 13 · 27.7%GRADE not reported 1 · 2.1%Very low 7 · 14.9%Low 19 · 40.4%Moderate 5 · 10.6%High 2 · 4.3%

Target of rapamycin inhibitors (TOR‐I) vs calcineurin inhibitors (CNI): secondary outcomes

Thrombocytopenia · primary immunosuppression in kidney transplant recipients

Target of rapamycin inhibitors (TOR‐I) may leads to higher thrombocytopenia compared with calcineurin inhibitors (CNI): secondary outcomes (low certainty).

1 finding from 1 review

Target of rapamycin inhibitors (TOR‐I) vs antimetabolites: secondary outcomes

Thrombocytopenia · primary immunosuppression in kidney transplant recipients

Target of rapamycin inhibitors (TOR‐I) may leads to higher thrombocytopenia compared with antimetabolites: secondary outcomes (low certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Thrombocytopenia · primary immunosuppression in kidney transplant recipients

Low may leads to lower thrombocytopenia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).

1 finding from 1 review

Intervention not reported

Heparin‐induced thrombocytopenia (HIT) · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower heparin‐induced thrombocytopenia (HIT) (low certainty).

1 finding from 1 review

Radioisotopes vs placebo

Safety (AE, adverse drug reaction): thrombocytopenia Grades 3 or 4 according to National Cancer Institute · patients with metastatic bone pain

Radioisotopes showed no clear difference in thrombocytopenia III‐IV compared with placebo (low certainty).

1 finding from 1 review

Carboplatin vs cisplatin chemotherapy

Safety (AE, adverse drug reaction): thrombocytopenia Grades 3 or 4 according to National Cancer Institute · combination with third‐generation drugs for advanced non‐small cell lung cancer

Carboplatin probably leads to higher grade III or IV thrombocytopenia compared with cisplatin chemotherapy (moderate certainty).

1 finding from 1 review