Findings

What do systematic reviews say?

26 questions · 36 findings · 16 reviews · Hypertension

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 16.7%Low 11 · 30.6%Moderate 15 · 41.7%High 4 · 11.1%

Intervention not reported

Systolic blood pressure · People with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
47 studies · 5246 participants
Low

Intervention not reported

Systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1007 participants
Low

Intervention not reported

Systolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 663 participants
Moderate

Intervention not reported

Systolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
47 studies · 7733 participants
High

Intervention not reported

Decrease in systolic blood pressure (mmHg) · alcohol consumers with high blood pressure

1 finding from 1 review

Alcohol intake reduction for controlling hypertension 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 269 participants
Very low

Calcium supplementation/fortification vs control

Systolic blood pressure · People who may be at risk for primary hypertension

2 findings from 1 review

Calcium supplementation for prevention of primary hypertension 2022 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 3140 participants
High
Calcium supplementation for prevention of primary hypertension 2022 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 452 participants
Moderate

Effect of high‐dose alcohol vs placebo

Systolic blood pressure · adult participants

3 findings from 1 review

Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 418 participants
Moderate
Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 54 participants
Moderate
Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 154 participants
Moderate

Effect of medium‐dose alcohol vs placebo

Systolic blood pressure · adult participants

3 findings from 1 review

Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 149 participants
Moderate
Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
54 participants
Low
Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 66 participants
Low

Effect of low‐dose alcohol vs placebo

Systolic blood pressure · adult participants

1 finding from 1 review

Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 28 participants
Low

Intervention not reported

Decrease in systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Weight‐reducing diets vs no weight‐reducing diets

Systolic blood pressure (mmHg), change from baseline · Men and non‐pregnant women ≥ 18 years old with essential hypertension

1 finding from 1 review

Long‐term effects of weight‐reducing diets in people with hypertension 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 731 participants
Low

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in systolic blood pressure (SBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).

4 findings from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term (follow-up 12 months) · People diagnosed with periodontitis
MD 0.14 [-4.4, 4.68]
1 study · 168 participants
Low
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Short term (follow-up 2-3 months) · People diagnosed with periodontitis
MD -0.14 [-4.05, 3.77]
2 studies · 294 participants
Low
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term (follow-up 6 months) · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
MD -2.25 [-9.41, 4.92]
2 studies · 108 participants
Low

Show 1 more finding

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Short term (follow-up 3 months) · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
MD 0.59 [-9.18, 10.36]
1 study · 55 participants
Very low

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in systolic blood pressure (SBP, mmHg) compared with supra-gingival scaling (moderate certainty).

3 findings from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Short term (follow-up 2 months) · People diagnosed with periodontitis and hypertension
MD -11.2 [-15.4, -7.0]
1 study · 101 participants
Moderate
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Short term (follow-up 2-3 months) · People diagnosed with periodontitis
MD -3.55 [-10.09, 2.98]
2 studies · 227 participants
Very low
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term (follow-up 6 months) · People diagnosed with periodontitis
MD -6.64 [-16.83, 3.55]
2 studies · 227 participants
Very low

Phentermine/topiramate vs placebo

Change in systolic blood pressure as compared to placebo [mm Hg] from baseline to end of study · Men and non‐pregnant women ≥ 18 years old with essential hypertension

1 finding from 1 review

Long‐term effects of weight‐reducing drugs in people with hypertension 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 772 participants
Low

Orlistat vs placebo

Change in systolic blood pressure as compared to placebo [mm Hg] from baseline to end of study · Men and non‐pregnant women ≥ 18 years old with essential hypertension

1 finding from 1 review

Long‐term effects of weight‐reducing drugs in people with hypertension 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2058 participants
Moderate

Walking vs no intervention

Systolic blood pressure · adults with or without hypertension

1 finding from 1 review

Walking for hypertension 2021 · Cochrane Headline outcomes only
no estimate extracted
73 studies · 5060 participants
Moderate

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Systolic blood pressure · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 767 participants
Low

Naltrexone/bupropion vs placebo

Change in systolic blood pressure as compared to placebo [mm Hg] from baseline to end of study · Men and non‐pregnant women ≥ 18 years old with essential hypertension

1 finding from 1 review

Long‐term effects of weight‐reducing drugs in people with hypertension 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 8283 participants
Moderate

Calcium supplementation/fortification vs control

Systolic blood pressure. 35 years or older (range of · People who may be at risk for primary hypertension

1 finding from 1 review

Calcium supplementation for prevention of primary hypertension 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 2688 participants
High

Intervention not reported

Systolic blood pressure clinical digital sphygmomanometer · adults with or without hypertension

1 finding from 1 review

Effect of cocoa on blood pressure 2017 · Cochrane Headline outcomes only
no estimate extracted
35 studies · 1804 participants
Moderate