Cochrane · systematic review · CD012787
Effect of alcohol on blood pressure
Tasnim, S, Tang, C, Musini, VM, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
21
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 9 · 42.9%Moderate 12 · 57.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Effect of high‐dose alcohol compared to placebo
Population: adult participants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic blood pressure ‐ ≤ 6 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 16 studies · 418 participants | Moderate Downgraded: risk of bias, imprecision |
Systolic blood pressure ‐ 7 to 12 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 3 studies · 54 participants | Moderate Downgraded: risk of bias, imprecision |
Systolic blood pressure ‐ ≥ 13 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 4 studies · 154 participants | Moderate Downgraded: risk of bias, imprecision |
Diastolic blood pressure ‐ ≤ 6 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 14 studies · 350 participants | Low Downgraded: risk of bias, imprecision |
Diastolic blood pressure ‐ 7 to 12 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 5 studies · 54 participants | Low Downgraded: risk of bias, imprecision |
Diastolic blood pressure ‐ ≥ 13 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 4 studies · 154 participants | Moderate Downgraded: risk of bias, imprecision |
Heart rate ‐ ≤ 6 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 17 studies · 495 participants | Moderate Downgraded: risk of bias, imprecision |
Heart rate ‐ 7 to 12 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 7 studies · 144 participants | Moderate Downgraded: risk of bias, imprecision |
Heart rate ‐ ≥ 13 hours Effect of high‐dose alcohol vs placebo | no estimate extracted | 8 studies · 244 participants | Moderate Downgraded: risk of bias, imprecision |
Effect of medium‐dose alcohol compared to placebo
Population: adult participants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic blood pressure ‐ ≤ 6 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 10 studies · 149 participants | Moderate Downgraded: risk of bias, imprecision |
Systolic blood pressure ‐ 7 to 12 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 54 participants | Low Downgraded: risk of bias, imprecision |
Systolic blood pressure ‐ ≥ 13 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 5 studies · 66 participants | Low Downgraded: risk of bias, imprecision |
Diastolic blood pressure ‐ ≤ 6 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 10 studies · 149 participants | Moderate Downgraded: risk of bias, imprecision |
Diastolic blood pressure ‐ 7 to 12 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 4 studies · 54 participants | Low Downgraded: risk of bias, imprecision |
Diastolic blood pressure ‐ ≥ 13 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 5 studies · 66 participants | Moderate Downgraded: risk of bias, imprecision |
Heart rate ‐ ≤ 6 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 12 studies · 181 participants | Moderate Downgraded: risk of bias, imprecision |
Heart rate ‐ 7 to 12 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 4 studies · 54 participants | Low Downgraded: risk of bias, imprecision |
Heart rate ‐ > 13 hours Effect of medium‐dose alcohol vs placebo | no estimate extracted | 3 studies · 36 participants | Low Downgraded: risk of bias, imprecision |
Effect of low‐dose alcohol compared to placebo
Population: adult participants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic blood pressure ‐ ≤ 6 hours Effect of low‐dose alcohol vs placebo | no estimate extracted | 2 studies · 28 participants | Low Downgraded: risk of bias |
Diastolic blood pressure ‐ ≤ 6 hours Effect of low‐dose alcohol vs placebo | no estimate extracted | 28 participants | Low Downgraded: risk of bias |
Heart rate ‐ ≤ 6 hours Effect of low‐dose alcohol vs placebo | no estimate extracted | 2 studies · 28 participants | Moderate Downgraded: risk of bias |