Intermittent ICS showed no clear difference in serious adverse events compared with placebo (moderate certainty).
Intermittent ICS showed no clear difference in serious adverse events compared with placebo (low certainty).
Intermittent 'as needed' ICS showed no clear difference in patients with serious adverse health events (duration 12 to 52 weeks) compared with daily ICS (low certainty).
Continuous showed no clear difference in serious adverse events compared with intermittent Antibiotic Infusions (low certainty).
28 days on/off antibiotic regimen showed no clear difference in serious adverse events compared with 28 days on/off placebo regimen (low certainty).
14 days on/off antibiotic regimen showed no clear difference in serious adverse events compared with 28 days on/off antibiotic regimen (moderate certainty).
14 days on/off antibiotic regimen showed no clear difference in serious adverse events compared with 14 days on/off placebo regimen (high certainty).