Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 34 findings · 13 reviews

No studies found 5 · 14.7%GRADE not reported 5 · 14.7%Very low 5 · 14.7%Low 16 · 47.1%Moderate 3 · 8.8%High 0 · 0%

High‐dose corticosteroids vs moderate‐dose or no corticosteroids

Serious adverse events · adults with metastatic extradural spinal cord compression (without peptic ulceration or infection; mixed prognosis)

High‐dose corticosteroids probably leads to higher serious adverse events compared with moderate‐dose or no corticosteroids (moderate certainty).

1 finding from 1 review