Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

449 questions · 459 findings · 247 reviews

No studies found 75 · 16.3%GRADE not reported 13 · 2.8%Very low 119 · 25.9%Low 139 · 30.3%Moderate 86 · 18.7%High 27 · 5.9%

Sulfasalazine vs placebo

Serious adverse events · Patients with ankylosing spondylitis

Sulfasalazine showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Allopurinol vs placebo

Serious adverse events · people with chronic gout

Allopurinol showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Ascorbic acid vs placebo

Serious adverse events · people with fatigue in peripheral neuropathy

Ascorbic acid showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Xiongshao capsule (XSC) plus conventional western medicine (CWM) vs conventional western medicine (CWM) plus placebo

Serious adverse events · patients with restenosis after percutaneous coronary intervention in coronary heart disease

Xiongshao capsule (XSC) plus conventional western medicine (CWM) leads to lower serious adverse events compared with conventional western medicine (CWM) plus placebo (high certainty).

1 finding from 1 review

Pregabalin vs placebo at end of treatment

Serious adverse events · patients with fibromyalgia

Pregabalin showed no clear difference in serious adverse events compared with placebo at end of treatment (moderate certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs placebo

Serious adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in serious Adverse Events compared with placebo (moderate certainty).

1 finding from 1 review

Febuxostat 120 mg/day vs placebo

Serious adverse events · patients with chronic cout

Febuxostat 120 mg/day showed no clear difference in serious Adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Febuxostat 40 mg/day vs placebo

Serious adverse events · people with chronic gout

Febuxostat 40 mg/day probably leads to higher serious Adverse Events compared with placebo (moderate certainty).

1 finding from 1 review