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What do systematic reviews say?

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Evidence found and GRADE certainty

143 questions · 144 findings · 68 reviews · Oral Health

No studies found 89 · 61.8%GRADE not reported 39 · 27.1%Very low 10 · 6.9%Low 1 · 0.7%Moderate 0 · 0%High 5 · 3.5%

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT

Quality of life · Adults (> 18 years) with peri-implant mucositis, receiving active treatment

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Quality of life · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Quality of life · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care

The review found no eligible studies for this question.

1 finding from 1 review

Chemotherapy (any regimen; added to, or compared with, locoregional treatment) vs Locoregional treatment and/or an alternative chemotherapy regimen

Quality of life · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning

Quality of life · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    Quality of life was a prespecified secondary outcome. None of the 44 included studies in the review (across all comparisons) reported quality-of-life data (review-wide evidence gap).
    0 studies
    No studies found

Amifostine vs no treatment/placebo

Quality of life · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Amifostine showed no clear difference in quality of life compared with no treatment/placebo; GRADE not reported.

1 finding from 1 review