Findings

What do systematic reviews say?

55 questions · 56 findings · 21 reviews · Urology

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No studies found 25 · 44.6%GRADE not reported 0 · 0%Very low 5 · 8.9%Low 12 · 21.4%Moderate 13 · 23.2%High 1 · 1.8%

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

Quality of life ‐ bowel function

1 finding from 1 review

Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 195 participants
Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

Quality of life ‐ sexual function

1 finding from 1 review

Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 195 participants
Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

Quality of life ‐ urinary function

1 finding from 1 review

Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 195 participants
Very low

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Quality of life · men with lower urinary tract symptoms secondary to benign prostatic obstruction

1 finding from 1 review

Transurethral microwave thermotherapy for the treatment of lower urinary tract symptoms in men with benign prostatic… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 136 participants
Moderate

Transurethral microwave thermotherapy vs sham

Quality of life · men with lower urinary tract symptoms secondary to benign prostatic obstruction

1 finding from 1 review

Transurethral microwave thermotherapy for the treatment of lower urinary tract symptoms in men with benign prostatic… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 347 participants
Low

Antibiotics vs placebo

Quality of life · participants with chronic prostatitis/chronic pelvic pain syndrome

1 finding from 1 review

Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 87 participants
Moderate

Convective radiofrequency water vapour thermal therapy vs sham

Quality of life · men with lower urinary tract symptoms suggesting benign prostatic hyperplasia

1 finding from 1 review

Convective radiofrequency water vapour thermal therapy for lower urinary tract symptoms in men with benign prostatic… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 195 participants
Moderate

Phytotherapy vs Another topical agent or placebo

Quality of life ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Penile traction therapy vs no treatment (short‐term)

Quality of life · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 82 participants
Very low

Targeted immunotherapy alone vs standard targeted therapies

Quality of life: improved to an important degree · previously treated patients with mRCC

Targeted immunotherapy alone probably leads to higher quality of life: Clinically relevant improvement in FKSI‐DRS compared with standard targeted therapies (moderate certainty).

2 findings from 1 review

Immunotherapy for metastatic renal cell carcinoma 2017 · Cochrane Headline outcomes only
RR 1.51 [1.28, 1.78]
1 study · 704 participants
Moderate
Immunotherapy for metastatic renal cell carcinoma 2017 · Cochrane Headline outcomes only
RR 1.37
1 study · 703 participants
Moderate

Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy

Disease‐specific quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care

Quality of life · adults with renal and ureteral stones undergoing shock wave lithotripsy

The review found no eligible studies for this question.

1 finding from 1 review

Alpha‐blockers after shock wave lithotripsy for renal or ureteral stones in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) vs ADT only

Quality of life at 12 months (

1 finding from 1 review

Taxane‐based chemohormonal therapy for metastatic hormone‐sensitive prostate cancer 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 790 participants
Low

Transrectal thermotherapy vs medical treatment

Quality of life ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extracorporeal shockwave therapy vs control procedure

Quality of life ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transrectal thermotherapy (add‐on) vs medical treatment

Quality of life ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Interferon‐α combined with targeted therapies vs standard targeted therapies

Quality of life · previously untreated patients with mRCC

The review found no eligible studies for this question.

1 finding from 1 review

Immunotherapy for metastatic renal cell carcinoma 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quality of life (Functional Assessment of Cancer Therapy‐prostate [FACT‐P; range 0 to 156; higher values = better quality of life]) measured at 12 months · men with metastatic, hormone‐sensitive prostate cancer

1 finding from 1 review

Abiraterone acetate in combination with androgen deprivation therapy compared to androgen deprivation therapy only for… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 838 participants
Moderate

Serenoa repens in combination with other phytotherapy vs placebo or no intervention

QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction

1 finding from 1 review

Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 265 participants
Very low

Immune checkpoint inhibitors vs any first‐line chemotherapy

Health‐related quality of life · participants with advanced or metastatic muscle invasive bladder cancer

1 finding from 1 review

Immunotherapy for advanced or metastatic urothelial carcinoma 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 393 participants
Moderate