Cochrane · systematic review · CD013393
Alpha‐blockers after shock wave lithotripsy for renal or ureteral stones in adults
Oestreich, MC, Vernooij, RWM, Sathianathen, NJ, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
UrologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Alpha‐blocker as adjuvant medical expulsive therapy plus usual care compared to usual care for renal and ureteral stones
Population: adults with renal and ureteral stones undergoing shock wave lithotripsy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Stone clearance assessed by imaging Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care | no estimate extracted | 36 studies · 4084 participants | Low Downgraded: risk of bias, inconsistency, publication bias |
Auxiliary treatment Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care | no estimate extracted | 12 studies · 1251 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Major adverse events determined by study investigators Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care | no estimate extracted | 7 studies · 747 participants | Low Downgraded: risk of bias |
Quality of life Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care | no estimate extracted | NR | No studies |
Stone clearance time measured in days Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care | no estimate extracted | 14 studies · 1790 participants | Low Downgraded: risk of bias, inconsistency, publication bias |