What do systematic reviews say?

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

• Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes

  1 year
  This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
  1 study · 26 participants
  Very low

Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy vs conventional therapy

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  6 months
  QoL measured with the Duke Health Profile; only within-group comparisons were provided; no score values, so a between-group analysis was not possible.
  1 study
  GRADE not reported

Low‐level laser therapy vs Placebo (sham) laser therapy

The review found no eligible studies for this question.

• Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
  Results: 'No studies reported on quality of life ...'. Not reported by the included laser trials.
  0 studies
  No studies found

CBT vs alternative treatment

The review found no eligible studies for this question.

• Psychological therapies for temporomandibular disorders (TMDs) 2022 · Cochrane All outcomes
  This outcome was not measured (not synthesised for this comparison; review-wide only one study reported quality of life).
  Studies not reported
  No studies found

CBT vs inactive control (usual care care, attention control, waitlist)

The review found no eligible studies for this question.

• Psychological therapies for temporomandibular disorders (TMDs) 2022 · Cochrane All outcomes
  This outcome was not measured for this comparison.
  Studies not reported
  No studies found

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

• Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes

  Baseline and 6 months
  no estimate extracted
  1 study · 49 participants
  GRADE not reported

Arthrocentesis and lavage vs Arthroscopy

The review found no eligible studies for this question.

• Arthrocentesis and lavage for treating temporomandibular joint disorders 2009 · Cochrane All outcomes
  No data about quality of life were reported by the included trials.
  0 studies
  No studies found

Stabilisation splint (SS) vs Non-occluding splint

Stabilisation splint (SS) led to lower quality of life compared with non-occluding splint; GRADE not reported.

• Stabilisation splint therapy for temporomandibular pain dysfunction syndrome 2004 · Cochrane All outcomes

  3 months or less
  RR 0.12 [0.02, 0.90]
  1 study
  GRADE not reported

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Occlusal splint led to lower participant satisfaction or quality of life compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes

  Short term (1 month) · Mixed TMD
  MD -7.56 [-14.50, -0.63]
  2 studies · 75 participants
  GRADE not reported

Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)

Occlusal splint showed no clear difference in participant satisfaction or quality of life compared with behavioural therapy (counselling, CBT, relaxation, self-care…; GRADE not reported.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes

  Short term (1 month) · Mixed TMD
  MD -1.42 [-15.78, 12.94]
  2 studies · 73 participants
  GRADE not reported