What do systematic reviews say?

Metoclopramide vs promethazine

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 149 participants
  Low

Metformin‐sulphonylurea (second‐ or third‐generation) combination therapy vs metformin plus another antidiabetic drug

The review found no eligible studies for this question.

• Metformin and second‐ or third‐generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin vs megestrol

The review found no eligible studies for this question.

• Metformin for endometrial hyperplasia 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Endometrial resection or ablation vs minimally invasive hysterectomy

• Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 145 participants
  Moderate

Summary of findings table ‐ Oral classical immunosuppressants (betamethasone) vs oral classical immunosuppressants (azathioprine, methotrexate, prednisolone)

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Metformin + megestrol vs megestrol

The review found no eligible studies for this question.

• Metformin for endometrial hyperplasia 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dexamethasone vs placebo

The review found no eligible studies for this question.

• Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy,… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metoclopramide vs ondansetron

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 160 participants
  Moderate

Methylprednisolone plus azathioprine vs methylprednisolone plus dapsone

The review found no eligible studies for this question.

• Interventions for bullous pemphigoid 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Methylphenidate vs placebo or no intervention

It is very uncertain whether methylphenidate changes quality of life (parent‐rated) compared with placebo or no intervention (very low certainty).

• Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD) 2023 · Cochrane Headline outcomes only
  SMD 0.4
  4 studies · 608 participants
  Very low

Rituximab (2 x 1000 mg) plus methotrexate vs methotrexate

Rituximab (2 x 1000 mg) plus methotrexate leads to higher health‐related quality of life compared with methotrexate monotherapy (high certainty).

• Rituximab for rheumatoid arthritis 2015 · Cochrane Headline outcomes only
  RR 2 [1.1, 3.4]
  4 studies · 1526 participants
  High

Grommets vs active monitoring

• Grommets (ventilation tubes) for recurrent acute otitis media in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 85 participants
  Low

Methotrexate vs other DMARDs

The review found no eligible studies for this question.

• Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Methotrexate vs placebo

The review found no eligible studies for this question.

• Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Thrombopoietin mimetics vs placebo

The review found no eligible studies for this question.

• Thrombopoietin mimetics for patients with myelodysplastic syndromes 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Injectional betamethasone vs Normal saline

The review found no eligible studies for this question.

• Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Methylxanthine derivatives vs inactive control

The review found no eligible studies for this question.

• Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pedometer intervention vs alternative physical activity intervention

The review found no eligible studies for this question.

• Workplace pedometer interventions for increasing physical activity 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Beclometasone/LABA vs LABA

• Beclometasone for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 465 participants
  Moderate

Dextromethorphan and quinidine sulfate combination (DMQ) vs placebo

The review found no eligible studies for this question.

• Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found