Cochrane · systematic review · CD012017
Grommets (ventilation tubes) for recurrent acute otitis media in children
Venekamp, RP, Mick, P, Schilder, AGM, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 36.4%Low 7 · 63.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Grommets versus active monitoring for recurrent acute otitis media in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of patients who have no AOM recurrences at 6 months post‐randomisation Grommets vs active monitoring | RR 9.49 [2.38, 37.8] | 1 study · 95 participants | Low Downgraded: risk of bias, imprecision |
Significant adverse effect: a tympanic membrane perforation persisting for 3 months or longer Grommets vs active monitoring | no estimate extracted | 1 study · 54 participants | Low Downgraded: risk of bias, imprecision |
Proportion of patients who have no AOM recurrences at 12 months post‐randomisation Grommets vs active monitoring | RR 1.41 [1, 1.99] | 1 study · 200 participants | Low Downgraded: risk of bias, imprecision |
Total number of AOM recurrences at 6 months post‐randomisation Grommets vs active monitoring | no estimate extracted | 1 study · 95 participants | Low Downgraded: risk of bias, imprecision |
Total number of AOM recurrences at 12 months post‐randomisation Grommets vs active monitoring | no estimate extracted | 1 study · 200 participants | Low Downgraded: risk of bias, imprecision |
Disease‐specific health‐related quality of life of the child at 4 and 12 months post‐randomisation using the OM‐6 questionnaire Grommets vs active monitoring | no estimate extracted | 1 study · 85 participants | Low Downgraded: risk of bias, imprecision |
Grommets versus antibiotic prophylaxis for recurrent acute otitis media in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of patients who have no AOM recurrences at 6 months post‐randomisation Grommets vs antibiotic prophylaxis | RR 1.68 [1.07, 2.65] | 2 studies · 96 participants | Very low Downgraded: risk of bias, imprecision |
Total number of AOM recurrences at 6 months post‐randomisation Grommets vs antibiotic prophylaxis | no estimate extracted | 1 study · 43 participants | Very low Downgraded: risk of bias, imprecision |
Grommets versus placebo medication for recurrent acute otitis media in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of patients who have no AOM recurrences at 6 months post‐randomisation Grommets vs placebo medication | RR 3.64 [1.2, 11.04] | 1 study · 42 participants | Very low Downgraded: risk of bias, imprecision |
Significant adverse effect: a tympanic membrane perforation persisting for 3 months or longer Grommets vs placebo medication | no estimate extracted | 1 study · 76 participants | Low Downgraded: risk of bias, imprecision |
Total number of AOM recurrences at 6 months post‐randomisation Grommets vs placebo medication | no estimate extracted | 1 study · 42 participants | Very low Downgraded: risk of bias, imprecision |