Cochrane · systematic review · CD012002
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery)
Vayne‐Bossert, P, Haywood, A, Good, P, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
1
No studies
4
Included studies
NR
No studies 4 · 80%Ungraded 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Dexamethasone compared to placebo for adult patients with advanced cancer who have nausea and vomiting (not related to chemo‐ or radiotherapy, or surgery)
Population: participants with advanced cancer who have nausea and vomiting not related to chemotherapy, radiotherapy, or surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea at 8 days Scale from: 0 to 10; lower score = less nausea. Dexamethasone vs placebo | no estimate extracted | 2 studies · 127 participants | Very low Downgraded: risk of bias, imprecision |
Number of vomiting episodes Dexamethasone vs placebo | no estimate extracted | NR | No studies |
Adverse events Dexamethasone vs placebo | no estimate extracted | NR | No studies |
Quality of life Dexamethasone vs placebo | no estimate extracted | NR | No studies |
Patient satisfaction Dexamethasone vs placebo | no estimate extracted | NR | No studies |