Findings

What do systematic reviews say?

8 questions · 8 findings · 6 reviews

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No studies found 1 · 12.5%GRADE not reported 4 · 50%Very low 1 · 12.5%Low 0 · 0%Moderate 2 · 25%High 0 · 0%

Bisphosphonates vs placebo/observation

Quality of life · women with advanced breast cancer without bone metastases

1 finding from 1 review

Bisphosphonates and other bone agents for breast cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 124 participants
Moderate

Bisphosphonates vs placebo/observation

Quality of life · women with metastatic breast cancer with bone metastases

1 finding from 1 review

Bisphosphonates and other bone agents for breast cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1888 participants
Moderate

Bisphosphonates vs placebo/no treatment

Quality of life · men with advanced prostate cancer

The review found no eligible studies for this question.

1 finding from 1 review

Bisphosphonates for advanced prostate cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bisphosphonates vs control

Quality of life · adults with GIOP

1 finding from 1 review

Bisphosphonates for steroid‐induced osteoporosis 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Bisphosphonates vs placebo

Number of participants with change in quality of life measures (not measured) · Paget's disease of bone

1 finding from 1 review

Bisphosphonates for Paget's disease of bone in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Bisphosphonates vs placebo or no treatment

Quality of life (change in mean back pain) · adults with β‐thalassaemia and osteoporosis

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Very low

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)

1 finding from 1 review

Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes
Baseline and 6 months
no estimate extracted
1 study · 49 participants
GRADE not reported

Zoledronate vs pamidronate or risedronate

Number of participants with change in quality of life measures (not measured) · Paget's disease of bone

1 finding from 1 review

Bisphosphonates for Paget's disease of bone in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported