Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

103 questions · 111 findings · 10 reviews

No studies found 9 · 8.1%GRADE not reported 26 · 23.4%Very low 25 · 22.5%Low 17 · 15.3%Moderate 23 · 20.7%High 11 · 9.9%

Bisphosphonates vs placebo

Number of participants who experienced side effects related to use of bisphosphonates · Paget's disease of bone

Bisphosphonates showed no clear difference in number of participants who experienced side effects related to use… compared with placebo (low certainty).

1 finding from 1 review