Findings

What do systematic reviews say?

249 questions · 267 findings · 154 reviews

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No studies found 32 · 12%GRADE not reported 32 · 12%Very low 72 · 27%Low 71 · 26.6%Moderate 54 · 20.2%High 6 · 2.2%

Oral antibiotics vs placebo

Change from baseline in quality of life IDQoL ranges from 0 to 30 with higher values indicating more impaired quality of life. · people with atopic dermatitis

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Moderate

Lay health worker‐led psychological interventions vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with common mental disorders

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 521 participants
Low

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Quality of life (mental component) (short‐term) SF‐36 physical component scale from 0 to 100 (higher is better quality of life). · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

Summary of findings: catgut implantation at acupoints plus antiepileptic drugs vs antiepileptic drugs alone

Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · people with epilepsy

1 finding from 1 review

Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
Low

Summary of findings: needle acupuncture vs sham

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · adults with intractable epilepsy

1 finding from 1 review

Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low

Summary of findings: needle acupuncture vs valproate

Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…

1 finding from 1 review

Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Low

Summary of findings: catgut implantation at acupoints vs valproate

Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · participants with generalised epilepsy

1 finding from 1 review

Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Low

Summary of findings: needle acupuncture plus valproate vs valproate

Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · participants with generalised epilepsy

1 finding from 1 review

Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Low

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life) · patients with fibromyalgia

Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).

1 finding from 1 review

Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia 2018 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 6861 participants
Low

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Quality of Life: SF‐36 (physical component) · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

Surgical vs non‐surgical treatment

Quality of Life: SF‐36 (physical component) · people aged over 14 years with displaced intra‐articular calcaneal fractures

1 finding from 1 review

Surgical versus non‐surgical interventions for displaced intra‐articular calcaneal fractures 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 192 participants
Low

Parent‐only interventions vs minimal contact control

Health‐related quality of life (HRQoL) · children with overweight or obesity

1 finding from 1 review

Parent‐only interventions for childhood overweight or obesity in children aged 5 to 11 years 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
GRADE not reported

ANY FORM OF PSYCHOEDUCATION vs usual care

Social functioning · Siblings of people with severe mental illness

1 finding from 1 review

Psychoeducation for siblings of people with severe mental illness 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Low

Intervention not reported

Quality of life (dyspnoea) Measured on the CRQ, the output is a number from 0 to 7, where higher on the scale is better. MID is 0.5. · adults with COPD who had exertional dyspnoea but did not fulfil the criteria for long‐term oxygen treatment

The intervention probably leads to higher quality of life (dyspnoea) Measured on the CRQ, the output is a… (moderate certainty).

1 finding from 1 review

Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest 2014 · Cochrane Headline outcomes only
MD 0.28 [0.1, 0.45]
4 studies · 341 participants
Moderate

Preoperative education vs usual care

Quality of Life: SF‐36 (physical component) · patients with knee replacement surgery

1 finding from 1 review

Preoperative education for hip or knee replacement 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 109 participants
Low

Intervention not reported

Health‐related quality of life SF‐36 scale: total score 0‐100, 8 subscales. Higher values mean better health‐related quality of life. · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1791 participants
Very low

Cemented vs uncemented hemiarthroplasty

HRQoL: using EQ‐5D (range from 0 to 1; higher values indicate better quality of life · adults with displaced and undisplaced hip fractures

1 finding from 1 review

Arthroplasties for hip fracture in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1122 participants
Moderate

Primary health professional‐led or collaborative care vs usual or enhanced care

Quality of life ‐ intermediate term (1 to 6 months post intervention) SF‐36 social functioning (higher score = higher quality of life) · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes quality of life ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
MD 3.5
1 study · 230 participants
Very low

Intervention not reported

General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

1 finding from 1 review

Surgical versus conservative interventions for treating anterior cruciate ligament injuries 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 121 participants
Low

Macrolides vs placebo

Health‐related quality of life (AQLQ)Scale from: 1‐7 (higher is better) · adults and children with chronic asthma

1 finding from 1 review

Macrolides versus placebo for chronic asthma 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 802 participants
Very low