Findings

What do systematic reviews say?

296 questions · 303 findings · 97 reviews

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No studies found 156 · 51.5%GRADE not reported 9 · 3%Very low 54 · 17.8%Low 48 · 15.8%Moderate 32 · 10.6%High 4 · 1.3%

Gabapentin vs pregabalin

Quality of life ‐ not reported · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Quality of life ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table (subcomparison 1): chemotherapy or targeted therapy plus best supportive care (BSC) vs BSC

Quality of life · palliative participants with esophageal and GE‐junction carcinoma

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1129 participants
Very low

UVA1 vs PUVA

Health‐related quality of life ‐ not measured · atopic eczema

The review found no eligible studies for this question.

1 finding from 1 review

Phototherapy for atopic eczema 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Ondansetron vs placebo

Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Montelukast vs placebo

Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs other antibiotics

Quality of life ‐ not reported · farmworkers

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for leptospirosis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo or no intervention

Quality of life ‐ not reported · farmworkers, soldiers, and people in endemic areas

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for leptospirosis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF

Quality of life at · adults with centre‐involving diabetic macular oedema

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with AC of the esophagus

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1772 participants
Very low

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with SCC of the esophagus

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Very low

Summary of findings ‐ nebulisers for delivering colistin and dornase alfa: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

Quality of life · children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ nebulisers for delivering other aerosolised medications: VMT and AAD tidal breathing mode (TBM) vs VMT and AAD target inhalation mode (TIM)

Quality of life · adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs macular laser

Quality of life at · adults with centre‐involving diabetic macular oedema

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal steroid

Quality of life at · adults with centre‐involving diabetic macular oedema

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: bevacizumab vs ranibizumab

No problems in quality of life domains at one year · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in no problems in quality of life domains at 1 year compared with ranibizumab (moderate certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration 2019 · Cochrane Headline outcomes only
RR 0.96 [0.9, 1.04]
1 study · 548 participants
Moderate

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with esophageal and GE‐junction carcinoma previously treated with chemotherapy

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1638 participants
Very low

Exercise vs control

Quality of life immediately after the intervention · people with Parkinson's disease

1 finding from 1 review

Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 951 participants
Low

Zinc sulphate vs placebo

Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise vs control (e.g. usual activities)

Health‐related quality of life · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

1 finding from 1 review

Exercise for preventing falls in older people living in the community 2019 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 3172 participants
Low