What do systematic reviews say?

Intervention not reported

• Drug interventions for the treatment of obesity in children and adolescents 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 86 participants
  Low

Psychological therapy vs enhanced or structured care

• Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 497 participants
  Moderate

Psychological therapy vs Waitlist/Usual Care

• Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 730 participants
  Low

Plasma‐derived C1 esterase inhibitor vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Low

Avoralstat vs placebo

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 93 participants
  Moderate

Intervention not reported

• Interventions to improve hearing aid use in adult auditory rehabilitation 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 35 participants
  Very low

Intervention not reported

• Interventions to improve hearing aid use in adult auditory rehabilitation 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 69 participants
  Low

Corticosteroids vs promethazine

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Endoscopy vs surgery

• Endoscopic or surgical intervention for painful obstructive chronic pancreatitis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Moderate

Dietary modifications (counselling or dietary change) vs control

• Dietary interventions for adults with chronic kidney disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 119 participants
  Low

Endoscopy vs surgery

• Endoscopic or surgical intervention for painful obstructive chronic pancreatitis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Moderate

Combinations of conservative treatments vs no treatment, sham treatment or verbal/written instruction

Combinations of conservative treatments showed no clear difference in condition‐specific quality of life: using validated questionnaires,… compared with no treatment, sham treatment or verbal/written instruction (moderate certainty).

• Conservative interventions for managing urinary incontinence after prostate surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 788 participants
  Moderate

Pelvic floor muscle training (PFMT) plus biofeedback vs no treatment, sham treatment or verbal/written instruction

The review found no eligible studies for this question.

• Conservative interventions for managing urinary incontinence after prostate surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Electrical or magnetic stimulation vs no treatment, sham treatment or verbal/written instruction

The review found no eligible studies for this question.

• Conservative interventions for managing urinary incontinence after prostate surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Augmentation of current antidepressant (various) with quetiapine (150 mg/d to 300 mg/d) vs augmentation of current antidepressant (various) with placebo

• Pharmacological interventions for treatment‐resistant depression in adults 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 884 participants
  Moderate

Spiritual practice vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mosaicplasty vs microfracture

It is very uncertain whether mosaicplasty changes quality of life: long‐term KOOS QOL score. Scale 0 to 100; higher… compared with microfracture (very low certainty).

• Surgical interventions (microfracture, drilling, mosaicplasty, and allograft transplantation) for treating isolated… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Natural products vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CBT vs control

• Psychological interventions for women with non‐metastatic breast cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  20 studies · 1747 participants
  Low