Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

701 questions · 713 findings · 246 reviews

No studies found 398 · 55.8%GRADE not reported 59 · 8.3%Very low 114 · 16%Low 98 · 13.7%Moderate 40 · 5.6%High 4 · 0.6%

Dietary supplements (hypericum perforatum / St John's Wort) vs placebo

QoL · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
  • Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
    short-term (up to 3 months) · hypericum perforatum
    Sardella 2008 (43 participants) evaluated QoL from patient self-reports and narratively indicated that both intervention and placebo participants were better able to cope at trial completion.
    1 study · 43 participants
    GRADE not reported

Educational intervention vs usual care or attention control

Global quality of life (at the end of the educational intervention) · patients with cancer‐related fatigue (adults)

Educational interventions showed no clear difference in global quality of life (at the end of the educational intervention) compared with control (usual care or attention control) (low certainty).

1 finding from 1 review