Question · asked by 1 review

Dietary supplements (hypericum perforatum / St John's Wort) vs placebo: QoL

Population
People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
Intervention
Dietary supplements (hypericum perforatum / St John's Wort)
Comparison
placebo
Outcome
QoL

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Dietary supplements (hypericum perforatum / St John's Wort) vs Placebo
Change in quality of life (QoL) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), hypericum perforatum
Interventions for treating burning mouth syndrome (2016) · Cochrane All outcomes
Sardella 2008 (43 participants) evaluated QoL from patient self-reports and narratively indicated that both intervention and placebo participants were better able to cope at trial completion.1 study · 43 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating burning mouth syndrome
2016 · Cochrane All outcomes
2015-12Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.