What do systematic reviews say?

Mindfulness‐based stress reduction training vs usual care

• Interventions to improve psychosocial well‐being in female BRCA‐mutation carriers following risk‐reducing surgery 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Very low

Intervention not reported

• Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 69 participants
  Very low

Multi‐component intervention vs control

• Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 374 participants
  Low

Oral hydroxychloroquine vs placebo

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Oral dehydroepiandrosterone vs placebo

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Oral chloroquine vs placebo

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Oral ciclosporin vs azathioprine (AZA)

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Oral methotrexate vs oral chloroquine

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Oral methotrexate vs placebo

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Brief psychotherapeutic intervention vs usual care

• Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 228 participants
  Moderate
• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 200 participants
  GRADE not reported

Intervention not reported

• Exercise interventions on health‐related quality of life for cancer survivors 2012 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 826 participants
  Low

Counselling vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Psychotherapy preceded by motivational interviewing vs psychotherapy alone

• Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 47 participants
  Very low

Surgery vs Pharmacological therapy

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

• Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting pituitary… 2024 · Cochrane Headline outcomes only
  MD 10
  1 study · 22 participants
  Low

Cognitive behavioural therapy as vs standard‐of‐care therapy

• Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Ball (stud) attachment system vs Bar attachment system

• Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws 2018 · Cochrane All outcomes
  Only Walton 2002 assessed patient satisfaction but reported narrative results and failed to provide any usable numbers. Quality of life as assessed by a validated measure was not recorded in any of the trials.
  1 study
  GRADE not reported

Ball (stud) attachment system vs Telescopic attachment system

• Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws 2018 · Cochrane All outcomes
  Cepa 2017 assessed patient satisfaction but did not use validated measures and we could not use the data. Quality of life as assessed by a validated measure was not recorded.
  1 study
  GRADE not reported

Ball (stud) attachment system vs Magnetic attachment system

• Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws 2018 · Cochrane All outcomes
  Two trials (Cune 2010; Naert 1999) reported patient satisfaction. However, we could not use any data from these studies. Quality of life as assessed by a validated measure was not recorded in any of the trials.
  2 studies
  GRADE not reported

Surgical vs non‐surgical treatment

Surgical showed no clear difference in quality of life: EQ‐5D (0: dead to 1: best quality of life) compared with non‐surgical treatment (high certainty).

• Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
  MD 0.01
  6 studies · 502 participants
  High